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Figure 2 | BMC Genetics

Figure 2

From: Filter-free exhaustive odds ratio-based genome-wide interaction approach pinpoints evidence for interaction in the HLA region in psoriasis

Figure 2

Power of different approaches to detect simulated epistatic interactions across the six epistasis models by Ritchie [ 28 ], in the presence of noise. Comparison of the power of four methods to detect interaction in the presence of one source of noise. GH: Genetic heterogeneity – GE: Genotyping errors – MS: Missing data – PC: Phenocopy. When GH is simulated, three different ways of calculating power are employed: the power of detecting both pairs in the same dataset, the power of detecting the first (fixed) pair and the power to detect either of the two epistatic pairs. Purple: FORCE – Green: MB-MDR – Blue: PLINK Epistasis – Red: PLINK FastEpistasis.

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BMC Genomic Data

ISSN: 2730-6844

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