Power of different approaches to detect simulated epistatic interactions across the six epistasis models by Ritchie [
], in the presence of noise. Comparison of the power of four methods to detect interaction in the presence of one source of noise. GH: Genetic heterogeneity – GE: Genotyping errors – MS: Missing data – PC: Phenocopy. When GH is simulated, three different ways of calculating power are employed: the power of detecting both pairs in the same dataset, the power of detecting the first (fixed) pair and the power to detect either of the two epistatic pairs. Purple: FORCE – Green: MB-MDR – Blue: PLINK Epistasis – Red: PLINK FastEpistasis.