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Figure 3 | BMC Genetics

Figure 3

From: Mechanisms of amino acid-mediated lifespan extension in Caenorhabditis elegans

Figure 3

Individual supplementation of many TCA cycle metabolites extends mean lifespan in C. elegans . (A) Succinate extends lifespan, (B) citrate does not extend lifespan, (C) alpha-ketoglutarate extends lifespan, and (D) isocitrate extends lifespan at one or more of the concentrations tested. 10 mM citrate is a standard component of the S-medium. It was removed to determine the effect of citrate on lifespan.

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