Skip to main content

Table 3 Stratified associations of SNPs rs11722228 and rs4148152 with CHD risk by CHD traditional risk factors

From: Associations of the uric acid related genetic variants in SLC2A9 and ABCG2 loci with coronary heart disease risk

 

rs11722228 ORs (95% CIs)

P

rs4148152 ORs (95% CIs)

 

Variables

CC

CT

TT

CT+TT

P

AA

AG

GG

AG+GG

P

Sex

          

  Male

1.00

1.07(0.86-1.33)

1.14(0.75-1.71)

1.08(0.87-1.33)

0.62

1.00

0.83(0.67-1.03)

0.83(0.58-1.21)

0.83(0.67-1.02)

0.86

  Female

1.00

1.19(0.78-1.81)

0.77(0.34-1.75)

1.12(0.75-1.68)

 

1.00

0.82(0.54-1.26)

0.71(0.34-1.46)

0.80(0.53-1.20)

 

BMI (kg/m2)

          

  <24

1.00

0.97(0.74-1.27)

1.14(0.68-1.91)

1.00(0.77-1.29)

0.55

1.00

0.82(0.62-1.07)

0.84(0.54-1.32)

0.82(0.64-1.07)

0.99

  ≥24

1.00

1.22(0.92-1.60)

1.01(0.61-1.68)

1.18(0.91-1.54)

 

1.00

0.86(0.65-1.14)

0.76(0.48-1.22)

0.84(0.65-1.10)

 

Smoking

          

  Yes

1.00

1.16(0.91-1.49)

1.23(0.77-1.97)

1.17(0.92-1.49)

0.23

1.00

0.82(0.64-1.06)

0.78(0.51-1.19)

0.82(0.64-1.04)

0.77

  No

1.00

1.01(0.74-1.37)

0.85(0.48-1.53)

0.98(0.73-1.32)

 

1.00

0.87(0.64-1.19)

0.86(0.51-1.45)

0.87(0.65-1.17)

 

Drinking

          

  Yes

1.00

0.88(0.62-1.26)

0.94(0.47-1.88)

0.89(0.64-1.25)

0.35

1.00

1.00(0.71-1.43)

0.82(0.42-1.56)

0.97(0.69-1.37)

0.47

  No

1.00

1.19(0.94-1.50)

1.09(0.71-1.67)

1.17(0.94-1.47)

 

1.00

0.79(0.63-1.00)

0.78(0.53-1.14)

0.79(0.63-0.99)a

 
  1. ORs and 95% CIs were obtained from logistic regression analyses with adjustment for age, sex, BMI, smoking, drinking and family history of CHD except for the stratified factor.
  2. a, OR is significant at the 0.05 level.
  3. P, for interactions of CHD traditional risk factors with rs11722228 and rs4148152.
Back to article page

BMC Genomic Data

ISSN: 2730-6844

Contact us