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Table 6 Analysis of variance performed on the average concordance rate and allelic R 2 of the animals in the imputation population from each scenario for imputation from low density panels to the 50K SNP panel 1,2

From: Accuracy of genome-wide imputation in Braford and Hereford beef cattle

Concordance rate

Allelic R 2

Source

Mean

Scheffé test 3

Source

Mean

Scheffé test 3

Algorithm 4 (P-value < 0.0001)

Algorithm 4 (P-value < 0.0001)

FImpute

1.340

a

FImpute

1.283

a

Beagle

1.306

b

Beagle

1.244

b

Panel 5 (P-value < 0.0001)

Panel 5 (P-value < 0.0001)

15K

1.402

a

15K

1.368

a

20K

1.347

b

20K

1.295

b

8K

1.345

c

8K

1.292

c

6K

1.332

d

6K

1.276

d

3K

1.189

e

3K

1.085

e

Scenario 6 (P-value 0.0147)

Scenario 6 (P-value 0.0277)

NE-P

1.323

a

NE-P

1.264

a

NNE-P

1.323

a

NE-NP

1.263

a

NE-NP

1.323

a

NNE-P

1.264

a

NNE-NP

1.322

a

NNE-NP

1.262

a

Algorithm*Panel (P-value < 0.0001)

Algorithm*Panel (P-value 0.0265)

FImpute - 15K

1.420

a

FImpute -15K

1.388

a

Beagle - 15K

1.384

b

Beagle - 15K

1.347

b

FImpute - 20K

1.365

c

FImpute - 20K

1.316

c

FImpute - 8K

1.362

d

FImpute - 8K

1.312

d

FImpute - 6K

1.349

e

FImpute - 6K

1.295

e

Beagle - 20K

1.330

f

Beagle - 20K

1.275

f

Beagle - 8K

1.328

f

Beagle - 8K

1.272

f

Beagle - 6K

1.316

g

Beagle - 6K

1.257

g

FImpute - 3K

1.204

h

FImpute - 3K

1.104

h

Beagle - 3K

1.174

i

Beagle - 3K

1.067

i

  1. 1Concordance rate and allelic R2 were arcsine square root transformed for the analyses;
  2. 2Interactions between Algorithm*Scenario and Panel*Scenario were not statistically significant (P > 0.05);
  3. 3Different letters within a group means that there is a statistical difference between two means (P < 0.05);
  4. 4Algorithm used was either FImpute v.2.2 [11] or Beagle v.3.3 [8];
  5. 53K, 6K, 8K, 15K and 20K are low-density panels;
  6. 6Scenarios for imputation to the 50K SNP panel. (NE-P) - using Nellore genotypes in the reference population and considering pedigree information; (NNE-P) - not using Nellore genotypes in the reference population and considering pedigree information; (NE-NP) - using Nellore genotypes in the reference population and not using pedigree information; (NNE-NP) - not using Nellore genotypes in the reference population and not using pedigree information.