Table 5 Impact of the rs7903146 SNP on anthropometric and glucose-related variables in non-T2D subjects, as a function of dessert intake
From: The TCF7L2rs7903146 polymorphism, dietary intakes and type 2 diabetes risk in an Algerian population
Non-/low consumers | Consumers/high consumers | ||||||||
|---|---|---|---|---|---|---|---|---|---|
Parameter | Interaction p | CC | CT | TT | p | CC | CT | TT | p |
N | 79 | 87 | 41 | 147 | 199 | 88 | |||
Weight (kg) | 0.41 | 72.5 ± 14.0 | 69.6 ± 15.5 | 66.5 ± 12.5 | 0.04 | 71.8 ± 14.0 | 71.2 ± 15.0 | 68.3 ± 14.8 | 0.18 |
BMI (kg/m2) | 0.83 | 26.5 ± 4.9 | 26.0 ± 5.3 | 24.7 ± 4.5 | 0.08 | 26.3 ± 5.1 | 25.6 ± 5.0 | 25.0 ± 5.3 | 0.06 |
Waist (cm) | 0.60 | 89.3 ± 12.6 | 86.0 ± 12.0 | 84.5 ± 11.8 | 0.06 | 87.5 ± 11.9 | 86.1 ± 12.3 | 84.2 ± 12.0 | 0.10 |
Hip (cm) | 0.87 | 102.0 ± 10.2 | 101.5 ± 9.0 | 99.9 ± 7.9 | 0.22 | 102.8 ± 9.4 | 101.6 ± 9.9 | 101.0 ± 10.8 | 0.13 |
Waist-to-hip ratio | 0.24 | 0.88 ± 0.09 | 0.85 ± 0.08 | 0.84 ± 0.08 | 0.07 | 0.85 ± 0.08 | 0.85 ± 0.08 | 0.83 ± 0.08 | 0.28 |
Fasting glucose (mmol/L) | 0.02 | 4.84 ± 0.49 | 4.81 ± 0.54 | 4.66 ± 0.53 | 0.29 | 4.78 ± 0.51 | 4.72 ± 0.48 | 4.89 ± 0.46 | 0.03 |
Fasting insulin (μIU/mL) | 0.24 | 9.27 ± 7.69 | 8.83 ± 6.94 | 6.40 ± 3.83 | 0.20 | 8.21 ± 6.05 | 7.51 ± 4.54 | 7.10 ± 4.08 | 0.99 |
HOMA-IR | 0.12 | 2.0 ± 1.5 | 1.9 ± 1.7 | 1.4 ± 0.9 | 0.16 | 1.8 ± 1.3 | 1.6 ± 1.0 | 1.6 ± 1.0 | 0.67 |
HOMA-B | 0.41 | 167.5 ± 189.6 | 150.9 ± 125.5 | 120.7 ± 72.9 | 0.77 | 157.3 ± 163.1 | 141.9 ± 106.0 | 111.6 ± 72.8 | 0.08 |