Table 1 Distributions of the 29 genotyped SNPs in the ISOR study
From: Combined effect of established BMI loci on obesity-related traits in an Algerian population sample
ISOR study | Speliotes et al. study | ||||||||
|---|---|---|---|---|---|---|---|---|---|
Nearby gene or locus | SNP | EA | OA | Genotype | p HWE | EAF/OAF | EAF/OAF | ||
0 | 1 | 2 | |||||||
FTO | rs9939609 | A | T | 278(0.37) | 370(0.49) | 106(0.14) | 0.33 | 0.39/0.61 | 0.42/0.58 |
TMEM18 | rs2867125 | C | T | 21(0.03) | 212(0.28) | 520(0.69) | 0.96 | 0.83/0.17 | 0.83/0.17 |
MC4R | rs571312 | A | C | 454(0.60) | 267(0.36) | 31(0.04) | 0.29 | 0.22/0.78 | 0.24/0.76 |
GNPDA2 | rs10938397 | G | A | 256(0.35) | 380(0.51) | 107(0.14) | 0.08 | 0.40/0.60 | 0.43/0.57 |
BDNF | rs10767664 | A | T | 31(0.04) | 219(0.29) | 496(0.67) | 0.29 | 0.81/0.19 | 0.78/0.22 |
NEGR1 | rs2815752 | A | G | 69(0.09) | 299(0.41) | 372(0.50) | 0.43 | 0.70/0.30 | 0.61/0.39 |
SH2B1 | rs7359397 | T | C | 547(0.73) | 186(0.25) | 17(0.02) | 0.82 | 0.15/0.85 | 0.40/0.60 |
ETV5 | rs9816226 | T | A | 40(0.05) | 252(0.34) | 448(0.61) | 0.59 | 0.78/0.22 | 0.82/0.18 |
MTCH2 | rs3817334 | T | C | 260(0.35) | 335(0.44) | 160(0.21) | 7.5×10-3 | 0.43/0.57 | 0.41/0.59 |
KCTD15 | rs29941 | G | A | 59(0.08) | 284(0.37) | 417(0.55) | 0.25 | 0.74/0.26 | 0.67/0.33 |
SEC16B | rs543874 | G | A | 522(0.69) | 220(0.29) | 18(0.02) | 0.41 | 0.17/0.83 | 0.19/0.81 |
TFAP2B | rs987237 | G | A | 552(0.73) | 176(0.23) | 28(0.04) | 4.0×10-3 | 0.15/0.85 | 0.18/0.82 |
FAIM2 | rs7138803 | A | G | 359(0.48) | 319(0.42) | 73(0.10) | 0.87 | 0.31/0.69 | 0.38/0.62 |
NRXN3 | rs10150332 | C | T | 455(0.61) | 256(0.34) | 38(0.05) | 0.76 | 0.22/0.78 | 0.21/0.79 |
RBJ | rs713586 | C | T | 203(0.27) | 375(0.51) | 163(0.22) | 0.74 | 0.47/0.53 | 0.47/0.53 |
GPRC5B | rs12444979 | C | T | 8(0.01) | 144(0.19) | 607(0.80) | 0.89 | 0.89/0.11 | 0.87/0.13 |
MAP2K5 | rs2241423 | G | A | 58(0.08) | 274(0.36) | 419(0.56) | 0.19 | 0.74/0.26 | 0.78/0.22 |
QPCTL | rs2287019 | C | T | 34(0.05) | 223(0.30) | 484(0.65) | 0.19 | 0.80/0.20 | 0.80/0.20 |
TNNI3K | rs1514175 | A | G | 229(0.30) | 358(0.47) | 170(0.23) | 0.19 | 0.46/0.54 | 0.43/0.57 |
SLC39A8 | rs13107325 | T | C | 730(0.96) | 33(0.04) | - | 0.54 | 0.02/0.98 | 0.07/0.93 |
FLJ35779 | rs2112347 | T | G | 78(0.11) | 298(0.40) | 364(0.49) | 0.15 | 0.69/0.31 | 0.63/0.37 |
LRRN6C | rs10968576 | G | A | 590(0.78) | 147(0.19) | 19(0.03) | 7.3×10-3 | 0.12/0.88 | 0.31/0.69 |
TMEM160 | rs3810291 | A | G | 209(0.28) | 356(0.47) | 190(0.25) | 0.16 | 0.49/0.51 | 0.67/0.33 |
PRKD1 | rs11847697 | T | C | 569(0.76) | 166(0.22) | 17(0.02) | 0.21 | 0.13/0.87 | 0.04/0.96 |
LRP1B | rs2890652 | C | T | 526(0.69) | 212(0.28) | 19(0.03) | 0.68 | 0.17/0.83 | 0.18/0.82 |
PTBP2 | rs1555543 | C | A | 238(0.32) | 378(0.51) | 129(0.17) | 0.32 | 0.43/0.57 | 0.59/0.41 |
MTIF3 | rs4771122 | G | A | 500(0.66) | 225(0.30) | 27(0.04) | 0.74 | 0.19/0.81 | 0.24/0.76 |
RPL27A | rs4929949 | C | T | 277(0.37) | 325(0.44) | 142(0.19) | 8.4×10-3 | 0.41/0.59 | 0.52/0.48 |
NUDT3 | rs206936 | G | A | 344(0.46) | 323(0.43) | 79(0.11) | 0.73 | 0.32/0.68 | 0.21/0.79 |