Figure 1

Shortest unrooted haplotype networks for HTR1A (left) and HTR1B (right). The networks represent all areas sequenced: coding regions and the areas flanking either side of the gene, including potential regulatory regions. Each circle represents a haplotype whose size is proportional to the frequency of the haplotype. The lengths of the lines connecting the circles are proportional (according to the scale provided) to the number of mutations that separate each haplotype. Because of the larger number of mutations separating the vervet from the macaques in HTR1B, this line (which represent 52 mutations) is not drawn to scale. Sulawesi species include M. nigra, M. tonkeana, and M. maura. For HTR1B, only the original M. nigra is shown (see Methods and Results).