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Table 1 Activities observed at XIST P2 region

From: Differentially methylated CpG island within human XIST mediates alternative P2 transcription and YY1 binding

 

DHS@

+P2 activity

++YY1 binding

+++DNA methylation

Male

-

-

-

78%

Female

+

+

+

44%

Xa Hybrid

-

-#

-

83%

Xi Hybrid

+

+*

+

7%

HT1080 XISTi

-

-

+

39%

Male hES

-**

-

-**

80%**

  1. @DHS: DNase Hypersensitive Site (from Figure 1; except for male hES (**) from UCSC).
  2. +P2 activity from RACE in Figure 2 or #[2]. *band observed with RACE, but not sequence-confirmed.
  3. ++YY1 binding from Figure 3, except ** from UCSC.
  4. +++DNA methylation is an average from 18 sites as shown in Figure 4.
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BMC Genomic Data

ISSN: 2730-6844

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