No penalty
|
---|
Haplotype
|
Frequency
|
Realizeda
|
Mean bias
|
Mean SE
|
Coverage
|
P < 0.05b
|
---|
001
|
0.050
|
1.094
|
-0.005
|
0.08
|
0.93
|
1.00
|
101
|
0.003
|
1.155
|
-0.037
|
0.38
|
0.93
|
0.77
|
010
|
0.020
|
0.016
|
-0.007
|
0.14
|
0.98
|
0.02
|
011
|
0.005
|
0.023
|
0.036
|
0.30
|
0.98
|
0.02
|
100
|
0.020
|
0.006
|
0.015
|
0.14
|
1.00
|
0.00
|
110
|
0.002
|
0.084
|
0.075
|
1.14
|
0.95
|
0.05
|
111
|
0.280
|
-0.007
|
-0.007
|
0.03
|
0.82
|
0.18
|
Ridge penalty
|
Haplotype
|
Frequency
|
Realizeda
|
Mean bias
|
Mean SE
|
Coverage
|
P < 0.05b
|
001
|
0.050
|
1.094
|
-0.009
|
0.07
|
0.91
|
1.00
|
101
|
0.003
|
1.155
|
-0.085
|
0.61
|
0.91
|
0.62
|
010
|
0.020
|
0.016
|
-0.007
|
0.013
|
0.96
|
0.04
|
011
|
0.005
|
0.023
|
0.046
|
0.23
|
0.96
|
0.04
|
100
|
0.020
|
0.006
|
0.014
|
0.12
|
0.98
|
0.02
|
110
|
0.002
|
0.084
|
0.067
|
0.40
|
0.66
|
0.34
|
111
|
0.280
|
-0.007
|
-0.008
|
0.03
|
0.81
|
0.19
|
Difference penalty
|
Haplotype
|
Frequency
|
Realizeda
|
Mean bias
|
Mean SE
|
Coverage
|
P < 0.05b
|
0 0 1
|
0.050
|
1.094
|
-0.011
|
0.07
|
0.88
|
1.00
|
1 0 1
|
0.003
|
1.155
|
-0.066
|
0.54
|
0.88
|
0.71
|
0 1 0
|
0.020
|
0.016
|
0.004
|
0.12
|
0.96
|
0.04
|
0 1 1
|
0.005
|
0.023
|
0.071
|
0.22
|
0.90
|
0.10
|
1 0 0
|
0.020
|
0.006
|
0.017
|
0.12
|
0.98
|
0.02
|
1 1 0
|
0.002
|
0.084
|
0.069
|
0.37
|
0.57
|
0.43
|
1 1 1
|
0.280
|
-0.007
|
-0.009
|
0.03
|
0.82
|
0.18
|
- a) "Realized" denotes to the median estimate from the simulated data, where the haplotypes were known, and could be used in the Cox model directly; b) For haplotypes 001 and 101 these percentages reflect power, whereas the percentages for the other five haplotypes reflect type I error probabilities.