No penalty
|
---|
Haplotype
|
Frequency
|
Realizeda
|
Mean bias
|
Mean SE
|
Coverage
|
P < 0.05b
|
---|
001
|
0.050
|
1.151
|
0.067
|
0.25
|
0.90
|
0.98
|
101
|
0.003
|
0.817
|
-0.868
|
8132.96
|
0.97
|
0.25
|
010
|
0.020
|
0.031
|
0.079
|
0.48
|
0.90
|
0.10
|
011
|
0.005
|
0.000
|
-1.363
|
3514.27
|
0.92
|
0.08
|
100
|
0.020
|
0.025
|
0.026
|
0.49
|
0.94
|
0.06
|
110
|
0.002
|
0.000
|
-1.082
|
13327.13
|
0.95
|
0.05
|
111
|
0.280
|
0.005
|
0.012
|
0.10
|
0.80
|
0.20
|
Ridge penalty
|
Haplotype
|
Frequency
|
Realizeda
|
Mean bias
|
Mean SE
|
Coverage
|
P < 0.05b
|
001
|
0.050
|
1.151
|
-0.012
|
0.24
|
0.84
|
0.99
|
101
|
0.003
|
0.817
|
-0.568
|
1.77
|
0.57
|
0.08
|
010
|
0.020
|
0.031
|
0.057
|
1.56
|
1.00
|
0.00
|
011
|
0.005
|
0.000
|
-0.322
|
2.91
|
0.98
|
0.02
|
100
|
0.020
|
0.025
|
0.022
|
1.65
|
1.00
|
0.00
|
110
|
0.002
|
0.000
|
-0.338
|
1.85
|
0.86
|
0.14
|
111
|
0.280
|
0.005
|
0.005
|
0.11
|
0.84
|
0.16
|
Difference penalty
|
Haplotype
|
Frequency
|
Realizeda
|
Mean bias
|
Mean SE
|
Coverage
|
P < 0.05b
|
0 0 1
|
0.050
|
1.151
|
0.003
|
0.25
|
0.88
|
0.98
|
1 0 1
|
0.003
|
0.817
|
-0.394
|
1.67
|
0.87
|
0.01
|
0 1 0
|
0.020
|
0.031
|
0.111
|
1.43
|
1.00
|
0.00
|
0 1 1
|
0.005
|
0.000
|
-0.049
|
2.48
|
0.99
|
0.01
|
1 0 0
|
0.020
|
0.025
|
0.078
|
1.53
|
1.00
|
0.00
|
1 1 0
|
0.002
|
0.000
|
-0.139
|
2.08
|
1.00
|
0.00
|
1 1 1
|
0.280
|
0.005
|
0.019
|
0.12
|
0.86
|
0.14
|
- a) "Realized" denotes to the median estimate from the simulated data, where the haplotypes were known, and could be used in the Cox model directly; b) For haplotypes 001 and 101 these percentages reflect power, whereas the percentages for the other five haplotypes reflect type I error probabilities.