A hierarchical and modular approach to the discovery of robust associations in genome-wide association studies from pooled DNA samples

Table 1 Summary of the results of Experiment 1.

Number of pools	Sample size	Average difference	Standard deviation	Correlation	Average error	Standard deviation	Correlation
2	30	0.0043	0.0303	0.9940	0.0304	0.0565	0.9860
2	45	0.0011	0.0295	0.9956	0.0331	0.0573	0.9890
2	60	0.0164	0.0498	0.9873	0.0451	0.0668	0.9890

Column 1: pool description; Column 2: number of samples per pool; Column 3: average difference between estimates of allele frequencies in repeated pools; Column 4: standard deviation of differences; Column 5: correlation between repeated allele frequency estimation. Column 6: average difference between estimates of allele frequencies from pooled DNA samples and individually genotyped samples. Column 7: standard deviation of the differences; Column 8: Correlation between estimates of allele frequencies from pooled DNA samples and individually genotyped samples.

ISSN: 2730-6844