|
Parameter
|
Genotypes
|
No.
|
Monocytes
|
Neutrophils
|
|---|
| | | |
*Low
|
High
|
Total
|
Low
|
High
|
Total
|
|---|
|
**C1291T
|
CC
|
28
|
29.57 ± 1.54
|
57.00 ± 1.81
|
86.57a ± 0.96
|
73.25 ± 2.52
|
4.48 ± 0.62
|
77.74 ± 2.73
|
| |
CT
|
30
|
28.25 ± 1.48
|
61.26 ± 1.75
|
89.51b ± 0.93
|
76.21 ± 2.43
|
5.54 ± 0.60
|
81.75 ± 2.64
|
| |
TT
|
6
|
32.02 ± 3.32
|
58.94 ± 3.91
|
90.97b ± 2.07
|
81.57 ± 5.43
|
4.11 ± 1.34
|
85.68 ± 5.91
|
|
A1908G (Asn175Asp)
|
AA
|
51
|
29.10 ± 1.14
|
59.12 ± 1.36
|
88.22 ± 0.74
|
75.25 ± 1.88
|
4.36A ± 0.43
|
79.60 ± 2.03
|
| |
AG
|
13
|
29.49 ± 2.26
|
59.39 ± 2.70
|
88.88 ± 1.47
|
76.09 ± 3.72
|
7.26B ± 0.86
|
83.35 ± 4.03
|
|
Haplotypes
|
CAAAG, CAAAG
|
28
|
29.57 ± 1.56
|
57.00 ± 1.82
|
86.57a ± 0.97
|
73.25 ± 2.55
|
4.48a ± 0.59
|
77.74 ± 2.78
|
| |
CAAAG, TAGGT
|
20
|
27.75 ± 1.84
|
62.46 ± 2.16
|
90.21b ± 1.14
|
77.36 ± 3.01
|
4.45a ± 0.70
|
81.81 ± 3.28
|
| |
CAAAG, TGGGT
|
10
|
29.24 ± 2.60
|
58.85 ± 3.05
|
88.09a ± 1.61
|
73.90 ± 4.26
|
7.73bc ± 0.98
|
81.63 ± 4.65
|
| |
TAGGT, TGGGT
|
3
|
30.33 ± 4.75
|
61.18 ± 5.56
|
91.51a ± 2.95
|
83.41 ± 7.78
|
5.68ab ± 1.80
|
89.08 ± 8.48
|
| |
TAGGT, TAGGT
|
3
|
33.72 ± 4.75
|
56.72 ± 5.56
|
90.42a ± 2.95
|
79.73 ± 7.78
|
2.55a ± 1.80
|
82.28 ± 8.48
|
- a, b, c or A, BMeans for each parameter and within the same column differ significantly. a, b, c indicates significance (P < 0.05) with non adjusted means while A, B indicate significance with both non-adjusted means and when Scheffe's adjustments were applied to means (P < 0.01). SNPs 1291, 2318 and 2601 are in 100% linkage disequilibrium and possess the same information, like wise are gene alleles and haplotypes. Only values for SNP1291 and haplotypes have been represented in the table.
- *Low indicates the percentage of cells in the region of Log101 to 102, high > log102 and total, all cells stained.
- **SNP numbering is according to GenBank No. EU148609 and amino acid residue numbering is according to GenBank No. ABV68569.
