TY - JOUR AU - Rankinen, T. AU - Zuberi, A. AU - Chagnon, Y. C. AU - Weisnagel, S. J. AU - Argyropoulos, G. AU - Walts, B. AU - Perusse, L. AU - Bouchard, C. PY - 2006 DA - 2006// TI - The human obesity gene map: the 2005 update JO - Obesity (Silver Spring, Md) VL - 14 UR - https://doi.org/10.1038/oby.2006.71 DO - 10.1038/oby.2006.71 ID - Rankinen2006 ER - TY - CHAP AU - Chiu, S. AU - Fisler, J. S. AU - Warden, C. H. ED - Fox, J. ED - Barthold, S. ED - Newcomer, C. ED - Smith, A. ED - Quimby, F. ED - Davisson, M. PY - 2006 DA - 2006// TI - Genetic Analysis of Rodent Obesity and Diabetes BT - The Mouse in Biomedical Research: Normative Biology, Husbandry, and Models ID - Chiu2006 ER - TY - JOUR AU - Wuschke, S. AU - Dahm, S. AU - Schmidt, C. AU - Joost, H. G. AU - Al-Hasani, H. PY - 2007 DA - 2007// TI - A meta-analysis of quantitative trait loci associated with body weight and adiposity in mice JO - International journal of obesity (2005) VL - 31 ID - Wuschke2007 ER - TY - JOUR AU - Farber, C. R. AU - Corva, P. M. AU - Medrano, J. F. PY - 2006 DA - 2006// TI - Genome-wide isolation of growth and obesity QTL using mouse speed congenic strains JO - BMC genomics [electronic resource] VL - 7 ID - Farber2006 ER - TY - JOUR AU - Farber, C. R. AU - Medrano, J. F. PY - 2007 DA - 2007// TI - Fine mapping reveals sex bias in quantitative trait loci affecting growth, skeletal size and obesity-related traits on mouse chromosomes 2 and 11 JO - Genetics VL - 175 UR - https://doi.org/10.1534/genetics.106.063693 DO - 10.1534/genetics.106.063693 ID - Farber2007 ER - TY - JOUR AU - Horvat, S. AU - Medrano, J. F. PY - 2001 DA - 2001// TI - Lack of Socs2 expression causes the high-growth phenotype in mice JO - Genomics VL - 72 UR - https://doi.org/10.1006/geno.2000.6441 DO - 10.1006/geno.2000.6441 ID - Horvat2001 ER - TY - JOUR AU - Corva, P. M. AU - Horvat, S. AU - Medrano, J. F. PY - 2001 DA - 2001// TI - Quantitative trait loci affecting growth in high growth (hg) mice JO - Mamm Genome VL - 12 UR - https://doi.org/10.1007/s003350010275 DO - 10.1007/s003350010275 ID - Corva2001 ER - TY - JOUR AU - Farber, C. R. AU - Medrano, J. F. PY - 2007 DA - 2007// TI - Dissection of a genetically complex cluster of growth and obesity QTLs on mouse chromosome 2 using subcongenic intercrosses JO - Mamm Genome VL - 18 UR - https://doi.org/10.1007/s00335-007-9046-0 DO - 10.1007/s00335-007-9046-0 ID - Farber2007 ER - TY - JOUR AU - Naggert, J. K. AU - Fricker, L. D. AU - Varlamov, O. AU - Nishina, P. M. AU - Rouille, Y. AU - Steiner, D. F. AU - Carroll, R. J. AU - Paigen, B. J. AU - Leiter, E. H. PY - 1995 DA - 1995// TI - Hyperproinsulinaemia in obese fat/fat mice associated with a carboxypeptidase E mutation which reduces enzyme activity JO - Nature genetics VL - 10 UR - https://doi.org/10.1038/ng0695-135 DO - 10.1038/ng0695-135 ID - Naggert1995 ER - TY - JOUR AU - Furuta, M. AU - Yano, H. AU - Zhou, A. AU - Rouille, Y. AU - Holst, J. J. AU - Carroll, R. AU - Ravazzola, M. AU - Orci, L. AU - Furuta, H. AU - Steiner, D. F. PY - 1997 DA - 1997// TI - Defective prohormone processing and altered pancreatic islet morphology in mice lacking active SPC2 JO - Proc Natl Acad Sci U S A VL - 94 UR - https://doi.org/10.1073/pnas.94.13.6646 DO - 10.1073/pnas.94.13.6646 ID - Furuta1997 ER - TY - JOUR AU - Lloyd, D. J. AU - Bohan, S. AU - Gekakis, N. PY - 2006 DA - 2006// TI - Obesity, hyperphagia and increased metabolic efficiency in Pc1 mutant mice JO - Human molecular genetics VL - 15 UR - https://doi.org/10.1093/hmg/ddl111 DO - 10.1093/hmg/ddl111 ID - Lloyd2006 ER - TY - JOUR AU - Berman, Y. AU - Mzhavia, N. AU - Polonskaia, A. AU - Devi, L. A. PY - 2001 DA - 2001// TI - Impaired prohormone convertases in Cpe(fat)/Cpe(fat) mice JO - J Biol Chem VL - 276 UR - https://doi.org/10.1074/jbc.M008499200 DO - 10.1074/jbc.M008499200 ID - Berman2001 ER - TY - JOUR AU - Laurent, V. AU - Kimble, A. AU - Peng, B. AU - Zhu, P. AU - Pintar, J. E. AU - Steiner, D. F. AU - Lindberg, I. PY - 2002 DA - 2002// TI - Mortality in 7B2 null mice can be rescued by adrenalectomy: involvement of dopamine in ACTH hypersecretion JO - Proc Natl Acad Sci U S A VL - 99 UR - https://doi.org/10.1073/pnas.261715099 DO - 10.1073/pnas.261715099 ID - Laurent2002 ER - TY - JOUR AU - Rockman, M. V. AU - Kruglyak, L. PY - 2006 DA - 2006// TI - Genetics of global gene expression JO - Nature reviews VL - 7 UR - https://doi.org/10.1038/nrg1964 DO - 10.1038/nrg1964 ID - Rockman2006 ER - TY - STD TI - The GeneNetwork. [http://www.genenetwork.org] UR - http://www.genenetwork.org ID - ref15 ER - TY - JOUR AU - Wang, J. AU - Williams, R. W. AU - Manly, K. F. PY - 2003 DA - 2003// TI - WebQTL: web-based complex trait analysis JO - Neuroinformatics VL - 1 UR - https://doi.org/10.1385/NI:1:4:299 DO - 10.1385/NI:1:4:299 ID - Wang2003 ER - TY - JOUR AU - Chesler, E. J. AU - Lu, L. AU - Shou, S. AU - Qu, Y. AU - Gu, J. AU - Wang, J. AU - Hsu, H. C. AU - Mountz, J. D. AU - Baldwin, N. E. AU - Langston, M. A. AU - Threadgill, D. W. AU - Manly, K. F. AU - Williams, R. W. PY - 2005 DA - 2005// TI - Complex trait analysis of gene expression uncovers polygenic and pleiotropic networks that modulate nervous system function JO - Nature genetics VL - 37 UR - https://doi.org/10.1038/ng1518 DO - 10.1038/ng1518 ID - Chesler2005 ER - TY - JOUR AU - Wang, S. AU - Yehya, N. AU - Schadt, E. E. AU - Wang, H. AU - Drake, T. A. AU - Lusis, A. J. PY - 2006 DA - 2006// TI - Genetic and genomic analysis of a fat mass trait with complex inheritance reveals marked sex specificity JO - PLoS genetics VL - 2 UR - https://doi.org/10.1371/journal.pgen.0020015 DO - 10.1371/journal.pgen.0020015 ID - Wang2006 ER - TY - JOUR AU - Wong, M. L. AU - Islas-Trejo, A. AU - Medrano, J. F. PY - 2002 DA - 2002// TI - Structural characterization of the mouse high growth deletion and discovery of a novel fusion transcript between suppressor of cytokine signaling-2 (Socs-2) and viral encoded semaphorin receptor (Plexin C1) JO - Gene VL - 299 UR - https://doi.org/10.1016/S0378-1119(02)01052-1 DO - 10.1016/S0378-1119(02)01052-1 ID - Wong2002 ER - TY - JOUR AU - Greenhalgh, C. J. AU - Bertolino, P. AU - Asa, S. L. AU - Metcalf, D. AU - Corbin, J. E. AU - Adams, T. E. AU - Davey, H. W. AU - Nicola, N. A. AU - Hilton, D. J. AU - Alexander, W. S. PY - 2002 DA - 2002// TI - Growth enhancement in suppressor of cytokine signaling 2 (SOCS-2)-deficient mice is dependent on signal transducer and activator of transcription 5b (STAT5b) JO - Mol Endocrinol VL - 16 UR - https://doi.org/10.1210/mend.16.6.0845 DO - 10.1210/mend.16.6.0845 ID - Greenhalgh2002 ER - TY - JOUR AU - Ehret, G. B. AU - Reichenbach, P. AU - Schindler, U. AU - Horvath, C. M. AU - Fritz, S. AU - Nabholz, M. AU - Bucher, P. PY - 2001 DA - 2001// TI - DNA binding specificity of different STAT proteins. Comparison of in vitro specificity with natural target sites JO - J Biol Chem VL - 276 UR - https://doi.org/10.1074/jbc.M001748200 DO - 10.1074/jbc.M001748200 ID - Ehret2001 ER - TY - JOUR AU - Woelfle, J. AU - Rotwein, P. PY - 2004 DA - 2004// TI - In vivo regulation of growth hormone-stimulated gene transcription by STAT5b JO - Am J Physiol Endocrinol Metab VL - 286 UR - https://doi.org/10.1152/ajpendo.00389.2003 DO - 10.1152/ajpendo.00389.2003 ID - Woelfle2004 ER - TY - JOUR AU - GuhaThakurta, D. AU - Xie, T. AU - Anand, M. AU - Edwards, S. W. AU - Li, G. AU - Wang, S. S. AU - Schadt, E. E. PY - 2006 DA - 2006// TI - Cis-regulatory variations: a study of SNPs around genes showing cis-linkage in segregating mouse populations JO - BMC genomics [electronic resource] VL - 7 ID - GuhaThakurta2006 ER - TY - STD TI - Mouse Phenome Database. [http://phenome.jax.org/pub-cgi/phenome/mpdcgi?rtn=docs/home] UR - http://phenome.jax.org/pub-cgi/phenome/mpdcgi?rtn=docs/home ID - ref24 ER - TY - JOUR AU - Bogue, M. A. AU - Grubb, S. C. AU - Maddatu, T. P. AU - Bult, C. J. PY - 2007 DA - 2007// TI - Mouse Phenome Database (MPD) JO - Nucleic acids research VL - 35 UR - https://doi.org/10.1093/nar/gkl1049 DO - 10.1093/nar/gkl1049 ID - Bogue2007 ER - TY - JOUR AU - Barrett, J. C. AU - Fry, B. AU - Maller, J. AU - Daly, M. J. PY - 2005 DA - 2005// TI - Haploview: analysis and visualization of LD and haplotype maps JO - Bioinformatics (Oxford, England) VL - 21 UR - https://doi.org/10.1093/bioinformatics/bth457 DO - 10.1093/bioinformatics/bth457 ID - Barrett2005 ER - TY - JOUR AU - Schmidt, G. AU - Sirois, F. AU - Anini, Y. AU - Kauri, L. M. AU - Gyamera-Acheampong, C. AU - Fleck, E. AU - Scott, F. W. AU - Chretien, M. AU - Mbikay, M. PY - 2006 DA - 2006// TI - Differences of pancreatic expression of 7B2 between C57BL/6J and C3H/HeJ mice and genetic polymorphisms at its locus (Sgne1) JO - Diabetes VL - 55 UR - https://doi.org/10.2337/diabetes.55.02.06.db05-0733 DO - 10.2337/diabetes.55.02.06.db05-0733 ID - Schmidt2006 ER - TY - JOUR AU - Sarac, M. S. AU - Windeatt, S. AU - Castro, M. G. AU - Lindberg, I. PY - 2002 DA - 2002// TI - Intrapituitary adenoviral administration of 7B2 can extend life span and reverse endocrinological deficiencies in 7B2 null mice JO - Endocrinology VL - 143 UR - https://doi.org/10.1210/endo.143.6.8811 DO - 10.1210/endo.143.6.8811 ID - Sarac2002 ER - TY - JOUR AU - Seidel, B. AU - Dong, W. AU - Savaria, D. AU - Zheng, M. AU - Pintar, J. E. AU - Day, R. PY - 1998 DA - 1998// TI - Neuroendocrine protein 7B2 is essential for proteolytic conversion and activation of proprotein convertase 2 in vivo JO - DNA and cell biology VL - 17 UR - https://doi.org/10.1089/dna.1998.17.1017 DO - 10.1089/dna.1998.17.1017 ID - Seidel1998 ER - TY - JOUR AU - Zhu, X. AU - Lindberg, I. PY - 1995 DA - 1995// TI - 7B2 facilitates the maturation of proPC2 in neuroendocrine cells and is required for the expression of enzymatic activity JO - J Cell Biol VL - 129 UR - https://doi.org/10.1083/jcb.129.6.1641 DO - 10.1083/jcb.129.6.1641 ID - Zhu1995 ER - TY - JOUR AU - Waha, A. AU - Koch, A. AU - Hartmann, W. AU - Milde, U. AU - Felsberg, J. AU - Hubner, A. AU - Mikeska, T. AU - Goodyer, C. G. AU - Sorensen, N. AU - Lindberg, I. AU - Wiestler, O. D. AU - Pietsch, T. AU - Waha, A. PY - 2007 DA - 2007// TI - SGNE1/7B2 is epigenetically altered and transcriptionally downregulated in human medulloblastomas JO - Oncogene VL - 26 UR - https://doi.org/10.1038/sj.onc.1210338 DO - 10.1038/sj.onc.1210338 ID - Waha2007 ER - TY - JOUR AU - Horvat, S. AU - Medrano, J. F. PY - 1995 DA - 1995// TI - Interval mapping of high growth (hg), a major locus that increases weight gain in mice JO - Genetics VL - 139 ID - Horvat1995 ER - TY - JOUR AU - Gentleman, R. C. AU - Carey, V. J. AU - Bates, D. M. AU - Bolstad, B. AU - Dettling, M. AU - Dudoit, S. AU - Ellis, B. AU - Gautier, L. AU - Ge, Y. AU - Gentry, J. AU - Hornik, K. AU - Hothorn, T. AU - Huber, W. AU - Iacus, S. AU - Irizarry, R. AU - Leisch, F. AU - Li, C. AU - Maechler, M. AU - Rossini, A. J. AU - Sawitzki, G. AU - Smith, C. AU - Smyth, G. AU - Tierney, L. AU - Yang, J. Y. AU - Zhang, J. PY - 2004 DA - 2004// TI - Bioconductor: open software development for computational biology and bioinformatics JO - Genome Biol VL - 5 UR - https://doi.org/10.1186/gb-2004-5-10-r80 DO - 10.1186/gb-2004-5-10-r80 ID - Gentleman2004 ER - TY - JOUR AU - Kerr, M. K. AU - Martin, M. AU - Churchill, G. A. PY - 2000 DA - 2000// TI - Analysis of variance for gene expression microarray data JO - J Comput Biol VL - 7 UR - https://doi.org/10.1089/10665270050514954 DO - 10.1089/10665270050514954 ID - Kerr2000 ER - TY - CHAP AU - Wu, H. AU - Kerr, M. AU - Cui, X. AU - Churchill, G. ED - Parmigiani, G. ED - Garett, E. S. ED - Irizarry, R. A. ED - Zeger, S. L. PY - 2002 DA - 2002// TI - MAANOVA: A Software Package for the Analysis of Spotted cDNA Microarray Experiments BT - The analysis of gene expression data: methods and software ID - Wu2002 ER - TY - STD TI - Bioconductor. [http://www.bioconductor.org] UR - http://www.bioconductor.org ID - ref36 ER - TY - JOUR AU - Benjamini, Y. AU - Hochberg, Y. PY - 1995 DA - 1995// TI - Controlling the False Discovery Rate: A Practical and Powerful Approach to Multiple Testing JO - Journal of the Royal Statistical Society Series B (Methodological) VL - 57 ID - Benjamini1995 ER - TY - JOUR AU - Broman, K. W. AU - Wu, H. AU - Sen, S. AU - Churchill, G. A. PY - 2003 DA - 2003// TI - R/qtl: QTL mapping in experimental crosses JO - Bioinformatics (Oxford, England) VL - 19 UR - https://doi.org/10.1093/bioinformatics/btg112 DO - 10.1093/bioinformatics/btg112 ID - Broman2003 ER - TY - CHAP PY - 2003 DA - 2003// BT - SAS OnlineDoc PB - SAS Institute Inc. CY - Cary, N.C. ID - ref39 ER - TY - JOUR AU - Lindberg, I. AU - van den Hurk, W. H. AU - Bui, C. AU - Batie, C. J. PY - 1995 DA - 1995// TI - Enzymatic characterization of immunopurified prohormone convertase 2: potent inhibition by a 7B2 peptide fragment JO - Biochemistry VL - 34 UR - https://doi.org/10.1021/bi00016a020 DO - 10.1021/bi00016a020 ID - Lindberg1995 ER - TY - JOUR AU - Hunter, W. M. AU - Greenwood, F. C. PY - 1962 DA - 1962// TI - Preparation of iodine-131 labelled human growth hormone of high specific activity JO - Nature VL - 194 UR - https://doi.org/10.1038/194495a0 DO - 10.1038/194495a0 ID - Hunter1962 ER - TY - JOUR AU - Fortenberry, Y. AU - Liu, J. AU - Lindberg, I. PY - 1999 DA - 1999// TI - The role of the 7B2 CT peptide in the inhibition of prohormone convertase 2 in endocrine cell lines JO - Journal of neurochemistry VL - 73 UR - https://doi.org/10.1046/j.1471-4159.1999.0730994.x DO - 10.1046/j.1471-4159.1999.0730994.x ID - Fortenberry1999 ER -