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Figure 6 | BMC Genetics

Figure 6

From: GpnmbR 150Xallele must be present in bone marrow derived cells to mediate DBA/2J glaucoma

Figure 6

IL18 levels do not become elevated in D2 aqueous humor or ciliary body. (A) IL18 levels in aqueous humor of age matched D2, D2-Gpnmb+, B6.Tyrp1bGpnmbR 150X, and C57BL/6J mice were determined by ELISA. IL18 levels are expressed as mean +/- SEM from 5 aqueous humor samples in each group. (B) Quantitative RT-PCR analysis comparing expression levels of IL18 transcript in ciliary body enriched dissections of 10.5 mo old D2, D2.Gpnmb+ and B6.Tyrp1bGpnmbR 150Xmice. The threshold cycle was calculated with normalization to Rn18s and values are expressed as mean +/- SEM, with 3–5 samples in each group.

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