TY - JOUR AU - Olshen, Adam B. AU - Gold, Bert AU - Lohmueller, Kirk E. AU - Struewing, Jeffery P. AU - Satagopan, Jaya AU - Stefanov, Stefan A. AU - Eskin, Eleazar AU - Kirchhoff, Tomas AU - Lautenberger, James A. AU - Klein, Robert J. AU - Friedman, Eitan AU - Norton, Larry AU - Ellis, Nathan A. AU - Viale, Agnes AU - Lee, Catherine S. AU - Borgen, Patrick I. AU - Clark, Andrew G. AU - Offit, Kenneth AU - Boyd, Jeff PY - 2008 DA - 2008/02/05 TI - Analysis of genetic variation in Ashkenazi Jews by high density SNP genotyping JO - BMC Genetics SP - 14 VL - 9 IS - 1 AB - Genetic isolates such as the Ashkenazi Jews (AJ) potentially offer advantages in mapping novel loci in whole genome disease association studies. To analyze patterns of genetic variation in AJ, genotypes of 101 healthy individuals were determined using the Affymetrix EAv3 500 K SNP array and compared to 60 CEPH-derived HapMap (CEU) individuals. 435,632 SNPs overlapped and met annotation criteria in the two groups. SN - 1471-2156 UR - https://doi.org/10.1186/1471-2156-9-14 DO - 10.1186/1471-2156-9-14 ID - Olshen2008 ER -