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Table 5 Correlation coefficients of hypertension-associated polymorphism MAFs with latitude.

From: Prevalence of common disease-associated variants in Asian Indians

Polymorphism

Population

Adjusted Spearman Rank Correlation Score

Adjusted r2

CYP3A5 g.6980G>A

CEPH-HGDP

-0.621**

0.319

 

CEPH-HGDP + HapMap

-0.620**

0.349

 

CEPH-HGDP + HapMap + AIP

-0.603**

0.302

AGT g.802C>T

CEPH-HGDP

-0.718**

0.409

 

CEPH-HGDP + Others

-0.693**

0.373

 

CEPH-HGDP + Others + AIP

-0.518**

0.248

GNB3 g.825C>T

Others

-0.620**

0.278

 

Others + AIP

-0.300*

0.101

  1. * significant at 0.05, ** significant at 0.01
  2. CEPH-HGDP = Centre d'Etude du Polymorphisme Humain-Human Genome Diversity Panel.
  3. AIP = Asian Indian population.
  4. Others = data from other populations that were not part of CEPH-HGDP or HapMap.
  5. For sample sizes, please see Additional file 1, Tables S4, S5, S6, for CYP3A5 g.6980G>A, AGT g.802C>T, and GNB3 g.825C>T, respectively.
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BMC Genomic Data

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