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Table 1 List of genes included in the study, with sequence screened and SNP frequency

From: Single nucleotide polymorphisms (SNPs) in coding regions of canine dopamine- and serotonin-related genes

Gene Gene symbol Gene product category/function* Bp screened SNP/bp
Dopamine related genes
Tyrosine hydroxylase TH Presynaptic form. of DOPA 1488 1/1488
Dopamine transporter SLC6A3 Synaptic clearance of Dopamine 1881 1/470
Dopamine receptor D1 DRD1 G protein-coupled receptor 1341 1/335
Dopamine receptor D2 DRD2 G protein-coupled receptor 1332 1/666
Dopamine receptor D3 DRD3 G protein-coupled receptor 1344 1/336
Norepinephrine related gene
Dopamine beta hydroxylase DBH Presynaptic form. of norepinephrine 1839 1/306
Serotonin related genes
5-hydroxytryptamine receptor 1A HTR1A G protein-coupled receptor 1272 1/1272
5-hydroxytryptamine receptor 1B HTR1B G protein-coupled receptor 1170 1/585
5-hydroxytryptamine receptor 1D HTR1D G protein-coupled receptor 1134 1/283
5-hydroxytryptamine receptor 1E HTR1E G protein-coupled receptor 1098 1/1098
5-hydroxytryptamine receptor 1F HTR1F G protein-coupled receptor 1101 1/1101
5-hydroxytryptamine receptor 2A HTR2A G protein-coupled receptor 1414 0
5-hydroxytryptamine receptor 2B HTR2B G protein-coupled receptor 1305 1/652
5-hydroxytryptamine receptor 2C HTR2C G protein-coupled receptor 1377 1/1377
5-hydroxytryptamine receptor 3A HTR3A Ligand-gated ion channel 1452 1/1452
5-hydroxytryptamine receptor 4 HTR4 G protein-coupled receptor 1167 0
Serotonin transporter SLC6A4 Synaptic clearance of Serotonin 1845 0
Tryptophan hydroxylase 1 TPH1 Presynaptic form. of hydroxytryptophan (5HT) 1335 0
Sum of bp screened    24895  
No. of SNPs detected    34  
Frequency of SNPs (snp/bp)    1/732  
   Synonym (n = 23)    1/1082  
   Non-synonym (n = 11)    1/2263  
  1. * As defined at [35]