Gene | Gene symbol | Gene product category/function* | Bp screened | SNP/bp |
---|---|---|---|---|
Dopamine related genes | ||||
Tyrosine hydroxylase | TH | Presynaptic form. of DOPA | 1488 | 1/1488 |
Dopamine transporter | SLC6A3 | Synaptic clearance of Dopamine | 1881 | 1/470 |
Dopamine receptor D1 | DRD1 | G protein-coupled receptor | 1341 | 1/335 |
Dopamine receptor D2 | DRD2 | G protein-coupled receptor | 1332 | 1/666 |
Dopamine receptor D3 | DRD3 | G protein-coupled receptor | 1344 | 1/336 |
Norepinephrine related gene | ||||
Dopamine beta hydroxylase | DBH | Presynaptic form. of norepinephrine | 1839 | 1/306 |
Serotonin related genes | ||||
5-hydroxytryptamine receptor 1A | HTR1A | G protein-coupled receptor | 1272 | 1/1272 |
5-hydroxytryptamine receptor 1B | HTR1B | G protein-coupled receptor | 1170 | 1/585 |
5-hydroxytryptamine receptor 1D | HTR1D | G protein-coupled receptor | 1134 | 1/283 |
5-hydroxytryptamine receptor 1E | HTR1E | G protein-coupled receptor | 1098 | 1/1098 |
5-hydroxytryptamine receptor 1F | HTR1F | G protein-coupled receptor | 1101 | 1/1101 |
5-hydroxytryptamine receptor 2A | HTR2A | G protein-coupled receptor | 1414 | 0 |
5-hydroxytryptamine receptor 2B | HTR2B | G protein-coupled receptor | 1305 | 1/652 |
5-hydroxytryptamine receptor 2C | HTR2C | G protein-coupled receptor | 1377 | 1/1377 |
5-hydroxytryptamine receptor 3A | HTR3A | Ligand-gated ion channel | 1452 | 1/1452 |
5-hydroxytryptamine receptor 4 | HTR4 | G protein-coupled receptor | 1167 | 0 |
Serotonin transporter | SLC6A4 | Synaptic clearance of Serotonin | 1845 | 0 |
Tryptophan hydroxylase 1 | TPH1 | Presynaptic form. of hydroxytryptophan (5HT) | 1335 | 0 |
Sum of bp screened | 24895 | |||
No. of SNPs detected | 34 | |||
Frequency of SNPs (snp/bp) | 1/732 | |||
Synonym (n = 23) | 1/1082 | |||
Non-synonym (n = 11) | 1/2263 |