Figure 1From: A mitochondrial mutator plasmid that causes senescence under dietary restricted conditionsPAL2-1 homologous mitochondrial plasmids abrogate the life span extending response to dietary restriction. Survival of near-isogenic lines derived from strain Wa32, with (red) and without (black) the pAL2-1 homologous plasmid pWa32-1, under regular (N, filled circles) and glucose-restricted (DR, open circles) conditions. As also previously shown [7], plasmid-carrying isolates respond less adequate to dietary restriction.Back to article page