|
Chromosome
|
Closest marker
|
Location (cM)
|
MLS (nominal p value)
|
|---|
| | | |
Single
|
Two-Locus Conditional on 6p21
|
|---|
| | | | |
Additive
|
General
|
|---|
|
1q23
|
D1S1653
|
160
|
0.77 (0.0467)
|
0.43 (0.1240)
|
1.19 (0.0470)
|
|
2q34-36
|
D2S163
|
214
|
1.03 (0.0240)
|
0.99 (0.0327)
|
1.21 (0.0443)
|
|
3p21
|
D3S1581
|
64
|
0.51 (0.0935)
|
1.25 (0.0173)
|
1.25 (0.0407)
|
|
4q21
|
D4S1534
|
97
|
0.64 (0.0658)
|
0.29 (0.1876)
|
1.10 (0.0564)
|
|
6p21
|
D6S1575
|
58
|
4.67 (0.000004)
|
NA NA
|
NA NA
|
|
6q13
|
D6S1557
|
82
|
1.52 (0.0071)
|
0.06 (0.4040)
|
0.06 (0.5990)
|
|
6q16
|
D6S1709
|
109
|
1.68 (0.0048)
|
0.97 (0.0260)
|
0.97 (0.0770)
|
|
7p15
|
D7S516
|
36
|
0.49 (0.0987)
|
1.45 (0.0112)
|
1.45 (0.0277)
|
|
9p13
|
D9S1817
|
59
|
1.56 (0.0064)
|
3.09 (0.0002)
|
3.09 (0.0004)
|
|
12q14
|
D12S83
|
76
|
0.77 (0.0467)
|
0.29 (0.1876)
|
1.40 (0.0294)
|
|
13q32
|
D13S1298
|
74
|
0.43 (0.1167)
|
0.02 (0.4667)
|
1.23 (0.0428)
|
|
14q24
|
D14S986
|
77
|
1.15 (0.0177)
|
0.65 (0.0724)
|
1.53 (0.0241)
|
|
15q22
|
D15S1036
|
54
|
1.35 (0.0108)
|
1.65 (0.0064)
|
1.65 (0.0186)
|
|
17p12
|
D17S799
|
32
|
2.12 (0.0017)
|
1.65 (0.0064)
|
2.14 (0.0061)
|
|
18p11
|
D18S1163
|
22
|
1.83 (0.0033)
|
1.05 (0.0282)
|
2.47 (0.0029)
|
|
18p11
|
D18S453
|
42
|
1.18 (0.0164)
|
0.71 (0.0617)
|
1.30 (0.0366)
|
|
18q12
|
D18S457
|
55
|
1.06 (0.0222)
|
0.66 (0.0706)
|
1.17 (0.0487)
|
- MLS was estimated using TWOLOCARP [38], the p value for a single-locus MLS was calculated using "possible triangle restriction" [39], and for a two-locus MLS obtained by Simulation.
- NA: not available
