TY - JOUR AU - Zhu, Chengsong AU - Zhang, Yuan-Ming PY - 2007 DA - 2007/11/29 TI - An EM algorithm for mapping segregation distortion loci JO - BMC Genetics SP - 82 VL - 8 IS - 1 AB - Chromosomal region that causes distorted segregation ratios is referred to as segregation distortion locus (SDL). The distortion is caused either by differential representation of SDL genotypes in gametes before fertilization or by viability differences of SDL genotypes after fertilization but before genotype scoring. In both cases, observable phenotypes are distorted for marker loci in the chromosomal region close to the SDL. Under the quantitative genetics model for viability selection by proposing a continuous liability controlling the viability of individual, a simplex algorithm has been used to search for the solution in SDL mapping. However, they did not consider the effects of SDL on the construction of linkage maps. SN - 1471-2156 UR - https://doi.org/10.1186/1471-2156-8-82 DO - 10.1186/1471-2156-8-82 ID - Zhu2007 ER -