Model | Dominant | Additive | Recessive |
|---|
Variant
|
P
|
OR (CI)
|
P
|
OR (CI)
|
P
|
OR (CI)
|
R702W
| 0.907 | 0.66 (0.0–104.2) | 0.940 | 1.03 (0.5–2.0) | 0.933 | 1.03 (0.5–2.2) |
G908R
| NA | NA | 0.255 | 0.50 (0.2–1.7) | 0.255 | 0.50 (0.2–1.7) |
1007fs
| 0.984 | NA | 0.245 | 0.63 (0.3–1.4) | 0.233 | 0.62 (0.3–1.4) |
- Logistic regression was performed under a dominant, an additive, and a recessive genetic disease model. The P values (P) are nominal (without further correction for multiple testing) and were obtained from a Wald for significant deviations of the regression parameter from 0. The odds ratio (OR) is given, including the 95% confidence interval (CI). Adjustment was done for the following confounders: gender, BMI, smoking status, diabetes status and high blood pressure status. NA, not applicable.