|
CARD15 variant
|
CHD
|
MI
|
Controls
|
P(CHD)
|
P(MI)
|
|---|
|
R702W (rs2066844)
| | | | | |
|
Number of individuals
|
890
|
589
|
632
| | |
|
Variant frequency
|
0.046
|
0.045
|
0.055
|
0.246
|
0.242
|
|
Genotype frequencies
| | | |
0.173
|
0.290
|
|
C/C
|
0.913
|
0.914
|
0.890
| | |
|
C/T
|
0.083
|
0.083
|
0.108
| | |
|
T/T
|
0.004
|
0.003
|
0.002
| | |
|
G908R (rs2066845)
| | | | | |
|
Number of individuals
|
900
|
596
|
632
| | |
|
Variant frequency
|
0.017
|
0.017
|
0.013
|
0.476
|
0.499
|
|
Genotype frequencies
| | | |
0.626
|
0.553
|
|
G/G
|
0.968
|
0.968
|
0.973
| | |
|
G/C
|
0.031
|
0.030
|
0.027
| | |
|
C/C
|
0.001
|
0.002
|
0.000
| | |
|
1007fs (rs2066847)
| | | | | |
|
Number of individuals
|
897
|
594
|
630
| | |
|
Variant frequency
|
0.027
|
0.030
|
0.026
|
0.736
|
0.892
|
|
Genotype frequencies
| | | |
0.489
|
0.583
|
|
-/-
|
0.945
|
0.939
|
0.942
| | |
|
-/insC
|
0.055
|
0.061
|
0.056
| | |
|
insC/insC
|
0.000
|
0.000
|
0.002
| | |
- Abbreviations: CHD, coronary heart disease; MI, myocard infarction; insC, cytosine insertion
