Figure 1From: Congenital syndactyly in cattle: four novel mutations in the low density lipoprotein receptor-related protein 4 gene (LRP4)Pedigree and LRP4 c.4863_4864delCGinsAT genotypes (A) and phenotype example (B) in Holstein family I. (A) Pedigree chart of the Holstein family I used in this study. Animals affected with syndactyly are shown as solid black symbols. Samples from animals with genotypes for LRP4 c.4863_4864delCGinsAT were available for the molecular genetic analyses. Notice that the genotypes do not always fit to the phenotypes assuming a recessive mode of inheritance. (B) Italian Holstein calf (VIII-4) with two affected syndactylous forefeet. Phenotypic data from the eight affected animals of generation II to VII were reported before [3].Back to article page