Table 4 Effect of SNPs showing a significant (p < 0.01) association with at least one cognitive trait at age 79 (LBC1921), controlling for sex and age 11 cognitive ability, on Raven's Progressive Matrices Score in later life controlling for sex, age 11 cognitive ability and cohort (ABC1936 or LBC1921).
| Â | Â | No. of subjects with each genotype | Raven's Progressive Matrices | ||||
|---|---|---|---|---|---|---|---|
Gene | SNP | A/A | A/B | B/B | F | p | η2 |
APP | rs2830102 | 79 | 381 | 415 | 5.988 | .003 | .014 |
GLRX | rs4561 | 323 | 424 | 127 | .846 | .429 | .002 |
HSPA9B | rs10117 | 133 | 433 | 323 | 1.528 | .217 | .003 |
MSRB2 | rs7427 | 106 | 396 | 386 | 1.443 | .237 | .003 |
NDUFS1 | rs11548670 | 829 | 56 | 1 | .533 | .587 | .001 |
NDUFV2 | rs906807 | 30 | 252 | 595 | 3.625 | .027 | .008 |
NDUFV3 | rs8128440 | 353 | 414 | 104 | .736 | .479 | .002 |