A genetic association analysis of cognitive ability and cognitive ageing using 325 markers for 109 genes associated with oxidative stress or cognition

Table 3 Effect of SNPs showing a significant (p < 0.01) association with at least one cognitive trait at age 79 (LBC1921), controlling for sex and age 11 cognitive ability, on cognitive traits at age 64 (ABC1936), controlling for sex and age 11 cognitive ability.

		No. of subjects with each genotype			BD	DS	RM	UCO	AVLT
Gene	SNP	A/A	A/B	B/B
APP	rs2830102	29	168	167	.380	.855	.345	.167	.984
GLRX	rs4561	128	171	66	.465	.426	.391	.044	.848
HSPA9B	rs10117	56	180	142	.433	.963	.012	.841	.698
MSRB2	rs7427	41	164	174	.451	.585	.813	.484	.650
NDUFS1	rs11548670	351	25	1	.570	.113	.956	.395	.144
NDUFV2	rs906807	11	102	256	.953	.749	.783	.410	.672
NDUFV3	rs8128440	145	178	41	.856	.903	.509	.146	.515

p values are given.
Key: BD = Block Design, DS = Digit Symbol, RM = Raven's Progressive Matrices, UCO = Use of Common Objects, AVLT = Auditory Verbal Learning Test

ISSN: 2730-6844