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Table 2 QTL for papilloma multiplicity

From: New chemically induced skin tumour susceptibility loci identified in a mouse backcross between FVB and dominant resistant PWK

   total female male
     Number of papillomas c)     
Marker Map location a) LRS P-value b) FF (Number of animals) FP (Number of animals) LRS P-value b) LRS P-value b)
Chromosome1            
   D1Mit18 21.4 7.4 0.00671* 6.33 ± 0.96 (103) 3.37 ± 0.56 (104) 8.9 0.00288* 0.9 >0.01
   D1Mit284 35.6 6.8 0.00924      9.4 0.00219* 0.9 >0.01
   D1Mit10 44.1 6.0 >0.01      8.4 0.00383* 0.7 >0.01
Chromosome2            
   D2Mit484 50 1.7 >0.01      8.1 0.00445* 0.2 >0.01
   D2Mit401 58.1 5.2 >0.01      8.9 0.00289* 0.5 >0.01
   D2Mit423 63.7 3.2 >0.01      8.8 0.00308* 0.0 >0.01
Chromosome3            
   D3mit40 36.1 7.6 0.0058* 6.39 ± 0.94 (109) 3.19 ± 0.54 (98) 3.6 >0.01 2.8 >0.01
Chromosome4            
   D4Mit235 3.3 7.4 0.00648* 6.56 ± 0.98 (98) 3.33 ± 0.57 (110)    4.1 >0.01
   D4Mit93 16.1 11.0 0.00092* 6.55 ± 0.94 (99) 3.31 ± 0.60 (109) 10.4 0.00123* 3.2 >0.01
   D4Mit111 22.1 12.5 0.00041* 6.57 ± 0.94 (99) 3.29 ± 0.61 (109) 8.8 0.00354* 4.8 >0.01
   D4Mit26 36.3 34.4 <0.00001*** 7.94 ± 1.05 (95) 2.11 ± 0.39 (109) 16.5 0.00005** 18.7 0.00002**
   D4Mit167 40 34.2 <0.00001*** 7.82 ± 1.01 (100) 2.11 ± 0.39 (108) 21.5 <0.00001*** 15.0 0.00011**
   D4Mit308 51.9 19.9 0.00001** 6.72 ± 0.86 (100) 3.12 ± 0.69 (108) 11.6 0.00067* 10.1 0.00147*
Chromosome11            
   D11Mit339 33.8 8.3 0.00388* 6.36 ± 0.92 (99) 3.48 ± 0.65 (109) 3.3 >0.01 5.3 >0.01
Chromosome12            
   D12Mit283 9.4 7.8 0.00534* 6.24 ± 0.92 (107) 3.39 ± 0.60 (101) 2.5 >0.01 4.6 >0.01
   D12Mit153 15.1 7.0 0.0081* 6.25 ± 0.93 (105) 3.44 ± 0.60 (102) 3.0 >0.01 3.3 >0.01
Chromosome14            
   D14Mit257 24.6        0.6 >0.01 9.4 0.00222*
   D14Mit203 44.1 8.4 0.00382* 6.18 ± 0.89 (100) 3.63 ± 0.68 (108) 1.8 >0.01 5.9 >0.01
   D14Mit193 48.3 12.3 0.00046* 6.43 ± 0.88 (103) 3.31 ± 0.67 (105) 1.8 >0.01 11.0 0.00089*
   D14Mit195 60.3 8.0 0.00465* 5.96 ± 0.78 (107) 3.68 ± 0.81 (101) 1.5 >0.01 6.2 >0.01
   D14Mit197 72.7        1.0 >0.01 8.0 0.00475*
Chromosome15            
   D15Mit15 64.9 3.4 >0.01      1.7 >0.01 10.6 0.0011*
   D15Mit161 68.8 4.8 >0.01      0.2 >0.01 9.1 0.0026*
  1. a) cM from the centrosome
  2. b) P-value for the association at each locus
  3. c) Data are shown as mean ± SEM.
  4. Values in parenthesis are number of samples.
  5. * Suggestive linkage
  6. ** Significant linkage
  7. *** Highly Significant linkage