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Table 2 QTL for papilloma multiplicity

From: New chemically induced skin tumour susceptibility loci identified in a mouse backcross between FVB and dominant resistant PWK

  

total

female

male

    

Number of papillomas c)

    

Marker

Map location a)

LRS

P-value b)

FF (Number of animals)

FP (Number of animals)

LRS

P-value b)

LRS

P-value b)

Chromosome1

           

   D1Mit18

21.4

7.4

0.00671*

6.33 ± 0.96

(103)

3.37 ± 0.56

(104)

8.9

0.00288*

0.9

>0.01

   D1Mit284

35.6

6.8

0.00924

    

9.4

0.00219*

0.9

>0.01

   D1Mit10

44.1

6.0

>0.01

    

8.4

0.00383*

0.7

>0.01

Chromosome2

           

   D2Mit484

50

1.7

>0.01

    

8.1

0.00445*

0.2

>0.01

   D2Mit401

58.1

5.2

>0.01

    

8.9

0.00289*

0.5

>0.01

   D2Mit423

63.7

3.2

>0.01

    

8.8

0.00308*

0.0

>0.01

Chromosome3

           

   D3mit40

36.1

7.6

0.0058*

6.39 ± 0.94

(109)

3.19 ± 0.54

(98)

3.6

>0.01

2.8

>0.01

Chromosome4

           

   D4Mit235

3.3

7.4

0.00648*

6.56 ± 0.98

(98)

3.33 ± 0.57

(110)

  

4.1

>0.01

   D4Mit93

16.1

11.0

0.00092*

6.55 ± 0.94

(99)

3.31 ± 0.60

(109)

10.4

0.00123*

3.2

>0.01

   D4Mit111

22.1

12.5

0.00041*

6.57 ± 0.94

(99)

3.29 ± 0.61

(109)

8.8

0.00354*

4.8

>0.01

   D4Mit26

36.3

34.4

<0.00001***

7.94 ± 1.05

(95)

2.11 ± 0.39

(109)

16.5

0.00005**

18.7

0.00002**

   D4Mit167

40

34.2

<0.00001***

7.82 ± 1.01

(100)

2.11 ± 0.39

(108)

21.5

<0.00001***

15.0

0.00011**

   D4Mit308

51.9

19.9

0.00001**

6.72 ± 0.86

(100)

3.12 ± 0.69

(108)

11.6

0.00067*

10.1

0.00147*

Chromosome11

           

   D11Mit339

33.8

8.3

0.00388*

6.36 ± 0.92

(99)

3.48 ± 0.65

(109)

3.3

>0.01

5.3

>0.01

Chromosome12

           

   D12Mit283

9.4

7.8

0.00534*

6.24 ± 0.92

(107)

3.39 ± 0.60

(101)

2.5

>0.01

4.6

>0.01

   D12Mit153

15.1

7.0

0.0081*

6.25 ± 0.93

(105)

3.44 ± 0.60

(102)

3.0

>0.01

3.3

>0.01

Chromosome14

           

   D14Mit257

24.6

      

0.6

>0.01

9.4

0.00222*

   D14Mit203

44.1

8.4

0.00382*

6.18 ± 0.89

(100)

3.63 ± 0.68

(108)

1.8

>0.01

5.9

>0.01

   D14Mit193

48.3

12.3

0.00046*

6.43 ± 0.88

(103)

3.31 ± 0.67

(105)

1.8

>0.01

11.0

0.00089*

   D14Mit195

60.3

8.0

0.00465*

5.96 ± 0.78

(107)

3.68 ± 0.81

(101)

1.5

>0.01

6.2

>0.01

   D14Mit197

72.7

      

1.0

>0.01

8.0

0.00475*

Chromosome15

           

   D15Mit15

64.9

3.4

>0.01

    

1.7

>0.01

10.6

0.0011*

   D15Mit161

68.8

4.8

>0.01

    

0.2

>0.01

9.1

0.0026*

  1. a) cM from the centrosome
  2. b) P-value for the association at each locus
  3. c) Data are shown as mean ± SEM.
  4. Values in parenthesis are number of samples.
  5. * Suggestive linkage
  6. ** Significant linkage
  7. *** Highly Significant linkage
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BMC Genomic Data

ISSN: 2730-6844

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