Figure 6

LD decay plots for the data generated in Group 3, with high LD, MAF> 0.05, and sporadic hotspots. The left panel displays the LD decay inferred by using the MLE (dashed lines) and the MAP approximation (continuous line), with α = 1. The line color represents four sample sizes: n = 60 (black); n = 120 (red); n = 240 (green); n ≥ 480 (dark blue). The right panel displays the LD decay for the same data based on the MAP approximation of D' with α = 0.25 (dashed lines) and α = 16 (continuous lines). The line color represents the sample size as in the left panel.