TY - JOUR AU - Zaki, Mehreen AU - King, Jason AU - Fütterer, Klaus AU - Insall, Robert H. PY - 2007 DA - 2007/06/06 TI - Replacement of the essential Dictyostelium Arp2 gene by its Entamoeba homologue using parasexual genetics JO - BMC Genetics SP - 28 VL - 8 IS - 1 AB - Cell motility is an essential feature of the pathogenesis and morbidity of amoebiasis caused by Entamoeba histolytica. As motility depends on cytoskeletal organisation and regulation, a study of the molecular components involved is key to a better understanding of amoebic pathogenesis. However, little is known about the physiological roles, interactions and regulation of the proteins of the Entamoeba cytoskeleton. SN - 1471-2156 UR - https://doi.org/10.1186/1471-2156-8-28 DO - 10.1186/1471-2156-8-28 ID - Zaki2007 ER -