Skip to main content
Figure 3 | BMC Genetics

Figure 3

From: Variation of the Myelin Oligodendrocyte Glycoprotein gene is not primarily associated with multiple sclerosis in the Sardinian population

Figure 3

Association analysis of 8 MOG variants with MS conditional on DRB1-DQB1 haplotypes using the Haplotype Method TDT Association analysis of 8 MOG variants with MS conditional on DRB1-DQB1 haplotypes using the Haplotype Method-Transmission Disequilibrium Test HM-TDT [39]. The 8 MOG variants are the same shown in Figure 1 while the 5 predisposing DRB1-DQB1 haplotypes refer to DRB1*0301-DQB1*0201 (2A), DRB1*0405-DQB1*0301 (2B), DRB1*1303-DQB1*0301(2C), DRB1*0405-DQB1*0302 (2D) and DRB1*1501-DQB1*0602 (2E), with DRB1*-DQB1* families negative for MS haplotypes that showed prior evidence of association with MS (2F) [13]. Association is presented as the negative log of the P-value for the extended transmission disequilibrium test (ETDT). The bold horizontal line corresponds to the threshold significance of 0.05

Back to article page

BMC Genomic Data

ISSN: 2730-6844

Contact us