Genetic fixity in the human major histocompatibility complex and block size diversity in the class I region including HLA-E

Romero, Viviana; Larsen, Charles E; Duke-Cohan, Jonathan S; Fox, Edward A; Romero, Tatiana; Clavijo, Olga P; Fici, Dolores A; Husain, Zaheed; Almeciga, Ingrid; Alford, Dennis R; Awdeh, Zuheir L; Zuñiga, Joaquin; El-Dahdah, Lama; Alper, Chester A; Yunis, Edmond J

doi:10.1186/1471-2156-8-14

Table 3 Haplotype statistical analysis for Panel 3, extending haplotypes into the complotype and HLA-DRB1 regions.

From: Genetic fixity in the human major histocompatibility complex and block size diversity in the class I region including HLA-E

HLA-A*	HLA-E*	HLA-Cw/B	Complotype	HLA-DRB1*	f¹	P²	HLA-E*	HLA-Cw/B	Complotype	HLA-DRB1*	f¹	P²
01	*0101*	*07, 08*	*SC01*	03	41/256	< 1 × 10^-7	*0101*	*07, 08*	*SC01*	03	48/258	1 × 10^-5
01	*0101*	*06, 57*	*SC61*	07	7/256	0.011	*0101*	*06, 57*	*SC61*	07	9/258	ns
02	*0101*	*07,07*	*SC31*	15	7/256	0.003	*0101*	*07,07*	*SC31*	15	8/258	ns
02	*0101*	*05, 44*	*SC30*	04	4/256	ns	*0101*	*05, 44*	*SC30*	04	4/258	ns
02	*0101*	*06, 50*	*S1C2(1,17)*	07	3/256	ns	*0101*	*06, 50*	*S1C2(1,17)*	07	4/258	ns
02	*010302*	*03,15*	*SC33*	04	2/256	ns	*010302*	*03,15*	*SC33*	04	2/258	ns
03	*0101*	*06,47*	*FC91,0*	07	2/256	ns	*0101*	*06,47*	*FC91,0*	07	2/258	ns
03	*010302*	*07, 07*	*SC31*	15	8/256	< 1 × 10^-7	*010302*	*07, 07*	*SC31*	15	9/258	0.022
11	*0101*	*04, 35*	*SC30*	01	2/256	ns	*0101*	*04, 35*	*SC30*	01	4/258	ns
23	*0101*	*04, 44*	*FC31*	07	5/256	1.1 × 10^-5	*0101*	*04, 44*	*FC31*	07	7/258	ns
24	*0101*	*08, 14*	*SC2(1,2)*	01	1/256	ns	*0101*	*08, 14*	*SC2(1,2)*	01	3/258	ns
25	*0101*	*12, 18*	*S042*	15	3/256	0.0007	*0101*	*12, 18*	*S042*	15	6/258	ns
26	*010301*	*12, 38*	*SC21*	04	9/256	< 1 × 10^-7	*010301*	*12, 38*	*SC21*	04	9/258	< 1 × 10^-7
29	*010302*	*16, 44*	*FC31*	07	11/256	< 1 × 10^-7	*010302*	*16, 44*	*FC31*	07	11/258	1.2 × 10^-5
30	*0101*	*06, 13*	*SC31*	07	4/256	0.0007	*0101*	*06, 13*	*SC31*	07	5/258	ns
30	*010302*	*05,18*	*F1C30*	03	10/256	< 1 × 10^-7	*010302*	*05,18*	*F1C30*	03	12/258	0.0002
33	*0101*	*03, 58*	*SC30*	03	1/256	ns	*0101*	*03, 58*	*SC30*	03	2/258	ns

¹Frequency (f)
²Probability (p)
Not significant (ns)

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