Table 3 Stratified analysis by smoking and occupational status for XRCC1 Arg280His polymorphism
From: DNA repair gene XRCC1 polymorphisms and bladder cancer risk
Exposure | status | Genotypes | Control (n) | Cases (n) | Crude OR (95%CI) | Adjusted OR (95%CI) | P value |
|---|---|---|---|---|---|---|---|
Smoking | Non-smoker | G/G | 174 | 103 | 1.00 | 1.00 | |
G/A + A/A | 16 | 12 | 1.27 (0.58–2.78) | 1.13 (0.50–2.56) | 0.77 | ||
Ex smoker | G/G | 253 | 244 | 1.00 | 1.00 | ||
G/A + A/A | 23 | 29 | 1.31 (0.74–2.32) | 1.30 (0.73–2.33) | 0.38 | ||
Current smoker | G/G | 89 | 108 | 1.00 | 1.00 | ||
G/A + A/A | 5 | 16 | 2.64 (0.93–7.48) | 2.52 (0.87–7.31) | 0.09 | ||
Occupation | No occupational exp | G/G | 429 | 327 | 1.00 | 1.00 | |
G/A + A/A | 35 | 43 | 1.61 (1.01–2.58) | 1.55 (0.96–2.51) | 0.07 | ||
Occupational exp | G/G | 87 | 129 | 1.00 | 1.00 | ||
G/A + A/A | 9 | 14 | 1.05 (0.43–2.53) | 1.03 (0.42–2.54) | 0.95 |