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Table 1 Empirical type I error rate of the proposed test at the nominal 5% level. A diallelic marker is completely linked to the QTL under HW equilibrium.

From: A quantitative linkage score for an association study following a linkage analysis

Effects 1

500 sibpairs

500 sibships 2

 

Linkage

Association-Linkage

Linkage

Association-Linkage

10%/80%

0.195

0.056

0.391

0.059

20%/70%

0.211

0.059

0.310

0.057

30%/60%

0.236

0.055

0.328

0.055

40%/50%

0.248

0.054

0.346

0.058

50%/40%

0.270

0.056

0.368

0.056

  1. 1 Common environmental & polygenic effects/individual random effects
  2. 2There are 200 sibships of size 2, 200 sibships of size 3 and 100 sibships of size 4.