BMC Genomic Data

Table 3 Summary statistics for the first simulation studies

From: Multinomial logistic regression approach to haplotype association analysis in population-based case-control studies

	Recessive Law			Dominant Law			Multiplicative Law
	β _X	β _hap	β _int	β _x	β _hap	β _int	β _x	β _hap	β _int
β_x= 0.3, β_hap= 0.1, β_int= 0
bias^a	0.000	-0.030	-0.002	-0.001	-0.003	0.004	0.003	0.000	-0.007
SE ^b	0.064	0.200	0.186	0.072	0.121	0.094	0.071	0.112	0.082
$\overline{SE}$ ^c	0.063	0.198	0.184	0.073	0.119	0.096	0.072	0.108	0.082
cover^d	0.944	0.945	0.948	0.955	0.950	0.957	0.959	0.943	0.946
size^e	-	-	0.053	-	-	0.043	-	-	0.054
β_X= 0.3, β_hap= 0.1, β_int= 0.15
bias^a	0.002	0.031	-0.011	0.001	0.006	0.000	0.003	-0.003	0.008
SE^b	0.061	0.196	0.183	0.075	0.120	0.099	0.075	0.104	0.085
$\overline{SE}$ ^c	0.063	0.199	0.180	0.073	0.120	0.094	0.072	0.109	0.079
cover^d	0.953	0.967	0.943	0.950	0.945	0.950	0.948	0.965	0.925
power^f	-	-	0.155	-	-	0.390	-	-	0.518
β_x= 0.3, β_hap= 0.1, β_int= 0.3
bias^a	0.000	-0.027	0.002	0.004	0.004	0.010	0.000	0.003	0.002
SE^b	0.067	0.204	0.168	0.074	0.112	0.089	0.070	0.110	0.074
$\overline{SE}$ ^c	0.063	0.201	0.174	0.074	0.121	0.093	0.072	0.111	0.076
cover^d	0.933	0.965	0.957	0.952	0.967	0.952	0.967	0.947	0.960
power^f	-	-	0.425	-	-	0.932	-	-	0.978

^aSimulation mean of the parameter estimates minus the true value.
^bSimulation standard error of the parameter estimates.
^cSimulation mean of the estimated standard errors.
^dCoverage probability of 95% confidence interval.
^eSize of Wald test for testing H₀ :β_int= 0.
^fPower of Wald test for testing H₀ : β_int= 0.

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