Table 3 Run-times. Average time per simulation, as a function of sample size n, based on 20 trials, assuming θ = 10-4/bp and ρ = 5 * 10-4/bp. Simulations were run on a 2.8 GHz Intel Xeon processor. Dashes correspond to simulations that could not be completed because they required too much (> 3 GB RAM) memory.