Figure 1From: Comparison of linkage and association strategies for quantitative traits using the COGA datasetLinkage and association analysis on chromosome 4. Graphical representation of analyzing the same markers for linkage and association analysis. The continuous line is a plot of the MERLIN LOD score p-value [plotted as -log(p-value)] by genetic location (in cM). The red symbols represent the p-values [plotted as -log(p-value)] of the five SNPs that were found to be most powerful using the PBAT screening strategy. The black dots represent the PBAT p-values for all other SNPs tested. The dotted horizontal reference line corresponds to the 5% significance level for the five most powerful PBAT SNPs, Bonferroni-adjusted for five tests (or the 0.01 significance level unadjusted).Back to article page