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Table 1 Results from the univariate methods

From: Selection of single-nucleotide polymorphisms in disease association data

  

rs1037475

rs1491233

  

χ 2

AA × HWD

Z 2 MERT

Z 2 MAX

χ 2

AA × HWD

Z 2 MERT

Z 2 MAX

Test statistic

 

9.299

19.685

4.234

8.842

0.620

1.301

0.380

0.616

p-value1

 

0.010

0.002

0.040

0.007

0.734

0.587

0.537

0.674

p-value2

Bon3

0.040

0.008

0.160

0.028

1.000

1.000

1.000

1.000

 

Holm

0.040

0.008

0.160

0.028

1.000

0.742

0.888

1.000

 

wy4

0.037

0.076

0.141

0.025

0.920

0.680

0.542

0.886

  

rs749407

rs980972

Test statistic

 

0.619

0.929

0.586

0.586

4.900

5.244

3.848

4.820

p-value1

 

0.734

0.371

0.444

0.684

0.086

0.136

0.050

0.060

p-value2

Bon3

1.000

1.000

1.000

1.000

0.344

0.544

0.200

0.240

 

Holm

1.000

0.742

0.888

1.000

0.258

0.408

0.160

0.180

 

wy4

0.730

0.526

0.670

0.689

0.234

0.224

0.135

0.156

  1. p-value1: Unadjusted p-value
  2. p-value2: Adjusted p-value
  3. Bon3: Bonferroni single-step correction
  4. wy4: Westfall and Young's maxT step-down correction.