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Table 2 Dominant Trait (B): 750 trios on averge

From: Impact of non-ignorable missingness on genetic tests of linkage and/or association using case-parent trios

 

Locus: C01R0052

Locus: C01R0001

 

Power %

Type I error %

 

NIM*

MAR**

NIM

MAR

TDTtrad

16.2

5.5

HRRtrad

16.4

5.3

TDTcomp

11.5

9.8

4.6

4.7

HRRcomp

11.4

10.0

4.4

4.6

1-TDT

20.4

12.5

5.1

4.8

EM-HRRdyads

23.5

14.1

4.3

4.4

EM-HRRall

22.8

14.2

4.4

4.6

  1. * Missing rate for each parent is approximately 30%.
  2. ** Each parent is missing randomly at the same rate of NIM.