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Table 1 Recessive trait (L): 120 trios on average

From: Impact of non-ignorable missingness on genetic tests of linkage and/or association using case-parent trios

 

Locus: C09R0765

Locus: C09R0850

 

Power %

Type I error %

 

NIM*

MAR**

NIM

MAR

TDTtrad

34.2

3.1

HRRtrad

34.2

3.0

TDTcomp

33.7

27.1

4.7

3.1

HRRcomp

33.6

27.1

5.4

3.0

1-TDT

39.5

31.7

4.5

2.9

EM-HRRdyads

44.2

31.9

3.9

3.1

EM-HRRall

42.3

32.1

3.3

3.3

  1. * Missing rate for each parent is approximately 10%.
  2. ** Each parent is missing randomly at the same rate of NIM.