Whole-genome association studies of alcoholism with loci linked to schizophrenia susceptibility

BMC Genomic Data

Table 1 The SNPs showing significant association located in major schizophrenia susceptibility candidate regions

Chr	SNP ID	Gene symbol	Cytoband	PDT p-value	Reported schizophrenia region^e
1	rs908857	DUSP10	1q41	0.0043^a	1q32.2-q41
	rs1053074-rs10594	KCNJ10	1q22-q23	0.0055^c	1q21-22
	tsc1457991-tsc1254625	PBX1	1q23	0.001^c	1q22-23
5	rs1229708	SPOCK	5q31	0.009^a	5q31
	tsc0935735	FER	5q21	0.0088^b	5q21-31
6	rs1498426	CDKAL1	6p22.3	0.006^b	6p22-24
	rs1022092	SLC16A10	6q21-q22	0.0039^b
	tsc0046065	PREP	6q22	0.0022^a	6q21-q22.3
	tsc0615608	AIM1	6q21	0.0087^c
	tsc0253130	TCBA1	6q21	0.0003^b (0.009)^d
8	tsc0149489-tsc0514918-tsc0529734	PTK2B	8p21.1	0.0056^c	8p21-22
	rs898249-rs900267-rs310319	BIN3	8p21.3	0.0053^c
10	rs729245	CACNB2	10p12	0.0009^a	10p11-15

^aAverage-PDT p-value
^bSum-PDT p-value
^cGenotype-PDT p-value
^dGEE p-value
^eData were brought from Michael et al.'s review article [2]. SNPs listed are located in genetic regions and showed allelic or genotypic association at 1% significance level. The schizophrenia susceptibility regions were identified by several independent linkage studies.

ISSN: 2730-6844