A comparison in association and linkage genome-wide scans for alcoholism susceptibility genes using single-nucleotide polymorphisms

Table 2 Comparisons of regions with peak NPL scores ≧ 1.5 by chromosomes using microsatellite and SNP markers.

	Microsatellite				SNP
Chr	Average information content	Peak NPL score	Position (cM)	1-LOD SI	Average information content	Peak NPL score	Position (cM)	1-LOD SI
1	0.78				0.91	1.75 ^a	77.15
						1.54	107.16
						1.95	142.09	[139.92, 152.58]
						1.92	274.27
2	0.78	2.23	4.9	[89.05, 133.01]	0.92	2.33	18.03
		2.24	94.2			3.72	90.60	[88.14, 95.20]
						2.99	112.07
						1.98	135.49
						2.59	244.44
3	0.71				0.91	1.70	60.44
						2.10	111.82
						2.13	144.53	[137.26, 144.57]
4	0.71				0.92	2.59	204.47	[204.32, 204.47]
5	0.74				0.92
6	0.67	1.56	112.9	[99.83, 127.70]	0.89	2.03	116.07	[110.71, 117.21]
						1.74	185.42
7	0.84	2.66	49.3	[40.96, 53.37]	0.92	1.74	13.65
		2.22	100.0	[82.55, 133.43]		2.72	31.68
						1.96	54.08
						2.81	101.05	[93.83, 107.52]
						2.04	123.79
8	0.76				0.92	2.24	21.97	[9.69, 24.13]
						2.14	42.16
9	0.68				0.91	2.13	141.17	[128.25, 151.24]
10	0.64				0.90	1.57	47.31
						2.85	106.69
						1.87	128.63
						3.08	171.41	[153.97, 175.87]
11	0.67	2.20	119.8	[99.24, 133.20]	0.92	2.44	125.15	[118.83, 130.89]
12	0.77	2.04	169.8	[154.18, 177.30]	0.91	2.08	86.43	[80.88, 88.63]
						1.64	122.16
13	0.74	1.49	97.3	[80.03, 113.50]	0.92	2.26	86.87	[83.80, 97.69]
14	0.72				0.91	1.66	23.73	[17.41, 25.95]
						1.66	88.50
15	0.75				0.91
16	0.69				0.89
17	0.66				0.89
18	0.65				0.91	2.19	106.82	[92.47, 111.48]
19	0.66				0.87
20	0.73				0.90	1.74	5.81	[0.16, 7.60]
21	0.76	1.66	62.7	[25.20, 62.70]	0.91
22	0.62				0.87	1.57	28.51	[22.77, 34.11]
23	0.82				0.91	3.21	42.78	[36.37, 43.43]
Overall average (SD)	0.74 (0.095)				0.91 (0.094)

^aGray text indicates local maximums in the region, while black text indicates the global maximum.

ISSN: 2730-6844