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Table 1 Comparisons of sex-specific distributions of linkage disequilibrium.

From: An exploration of sex-specific linkage disequilibrium on chromosome X in Caucasians from the COGA study

 

Intercept

*Sexa

Regiona

Distance (cM)

Scale

Shape

A. Chromosome X-Females vs. Males

-2.0340

-0.0092

-b

-0.2799

2.1870

0.4573

SE()

0.1375

0.1725

-

0.1025

0.0684

0.0143

χ2

218.82

0

-

7.45

-

-

P

<0.0001

0.9573

-

0.0063

-

-

B. Chromosome X-PAR1 vs. Heterosomal

-1.9951

-

-3.2261

-0.6541

2.2447

0.4455

SE()

0.1899

-

1.1347

0.2532

0.1218

0.0242

χ2

110.4

-

8.08

6.68

-

-

P

<0.0001

-

0.0045

0.0098

-

-

C. Females-Chromosome X vs. Autosomes

-1.5356

-

-0.9522

-1.0045

2.1099

0.4740

SE()

0.1228

-

0.1235

0.0177

0.0134

0.0030

χ2

156.40

-

59.45

3210.72

-

-

P

<0.0001

-

<0.0001

<0.0001

-

-

D. Males-Chromosome X vs. Autosomes

-1.7596

-

-0.5890

-0.6457

1.9684

0.5080

SE()

0.1065

-

0.1074

0.0149

0.0125

0.0032

χ2

273.2

-

30.09

1872.87

-

-

p

<0.0001

-

<0.0001

<0.0001

-

-

E. Females-PAR1 vs. Autosomes

-5.1301

-

2.6487

-1.0247

2.1055

0.4749

SE()

1.0528

-

1.0529

0.0172

0.0135

0.0030

χ2

23.75

-

6.33

3552.71

-

-

p

<0.0001

-

0.0119

<0.0001

-

-

  1. aFor the comparison of sex on chromosome X, males were coded as zero and females coded as 1. For the (females-only) comparison of regions on chromosome X, the heterosomal markers were coded as 0 and PAR1 coded as 1. For the sex-specific comparisons of chromosome X to the autosomes, the autosomes were coded as 0 and chromosome X coded as 1.
  2. b-, not done.