TY - JOUR AU - Marroni, Fabio AU - Toni, Chiara AU - Pennato, Benedetto AU - Tsai, Ya-Yu AU - Duggal, Pryia AU - Bailey-Wilson, Joan E. AU - Presciuttini, Silvano PY - 2005 DA - 2005/12/30 TI - Haplotypic structure of the X chromosome in the COGA population sample and the quality of its reconstruction by extant software packages JO - BMC Genetics SP - S77 VL - 6 IS - 1 AB - The haplotypes of the X chromosome are accessible to direct count in males, whereas the diplotypes of the females may be inferred knowing the haplotype of their sons or fathers. Here, we investigated: 1) the possible large-scale haplotypic structure of the X chromosome in a Caucasian population sample, given the single-nucleotide polymorphism (SNP) maps and genotypes provided by Illumina and Affimetrix for Genetic Analysis Workshop 14, and, 2) the performances of widely used programs in reconstructing haplotypes from population genotypic data, given their known distribution in a sample of unrelated individuals. SN - 1471-2156 UR - https://doi.org/10.1186/1471-2156-6-S1-S77 DO - 10.1186/1471-2156-6-S1-S77 ID - Marroni2005 ER -