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Table 2 Multipoint linkage analysis ordered by number of tagSNPs for the chromosome 21 region.

From: Identification of tag single-nucleotide polymorphisms in regions with varying linkage disequilibrium

  # of SNPs LOD score (p-value) simulated trait (chromosome 21) rs2835626 LOD Score (p-value) simulated trait (chromosome 20) tsc0041859 Mean information content
SNPtagger/HTSNP a 4 11.44 (<0.00001) 0.03 (0.4) 0.58
Nyholt 5 11.70 (<0.00001) 0.17 (0.2) 0.60
TagSNP 5 12.03 (<0.00001) 0.15 (0.2) 0.60
Haploview 6 12.42(<0.00001) 0.30 (0.12) 0.62
HB Finder 7 12.63 (<0.00001) 0.80 (0.03) 0.61
Mengb 8 13.27 (<0.00001) 1.08 (0.013) 0.60
All SNPs 17 13.50(<0.00001) 0.86 (0.02) 0.69
  1. aBold, program included the simulated trait on chromosome 21.
  2. bBlack, program _______________________________.