TY - JOUR AU - Papanicolaou, George J. AU - Justice, Cristina M. AU - Kovac, Illija M. AU - Sorant, Alexa JM AU - Wilson, Alexander F. PY - 2005 DA - 2005/12/30 TI - Critical values and variation in type I error along chromosomes in the COGA dataset using the applied pseudo-trait method JO - BMC Genetics SP - S54 VL - 6 IS - 1 AB - By analyzing a "pseudo-trait," a trait not linked or associated with any of the markers tested, the distribution of the test statistic under the null hypothesis can provide the critical value for the appropriate percentile of the distribution. In addition, the anecdotal observation that p-values tend to be more significant near the telomeres was investigated. SN - 1471-2156 UR - https://doi.org/10.1186/1471-2156-6-S1-S54 DO - 10.1186/1471-2156-6-S1-S54 ID - Papanicolaou2005 ER -