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Table 2 Chromosome 1 empirical maximum multipoint LOD score cutpoints.

From: Comparison of single-nucleotide polymorphisms and microsatellites in detecting quantitative trait loci for alcoholism: The Collaborative Study on the Genetics of Alcoholism

 

LOD score

P-valuea

Microsatelliteb

SNP1b

SNP2c

0.1

1.29

1.53

1.44

0.05

1.48

1.85

1.69

0.01

1.98

2.46

2.25

0.005

2.07

2.72

2.54

  1. aChromosome 1 P = 0.004 corresponds to genome-wide P = 0.05.
  2. bBased on 500 simulations.
  3. cBased on 200 simulations.