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Table 2 Comparison of linkage analysis results and genetic effect estimates for the naïve and three bootstrap estimates using microsatellite markers and SNPs.

From: Resampling methods to reduce the selection bias in genetic effect estimation in genome-wide scans

       Bootstrap estimate (bias)
Replicate Population Chromosome Highest peak (cM) True genetic effect T/F positive
Microsatellite Markers          
1 DA 1 169.97 0.49 ± 0.10 T 0.55 (0.06) 0.50 (0.01) 0.48 (-0.01) 0.47 (-0.03)
1 AI 3 294.68 0.33 ± 0.16 T 0.43 (0.10) 0.31 (-0.01) 0.25 (-0.08) 0.19 (-0.13)
1 KA 9 2.76 0.43 ± 0.11 T 0.49 (0.06) 0.40 (-0.04) 0.34 (-0.09) 0.24 (-0.19)
35 DA 6 192.09 -0.01 ± 0.11 F 0.41 (0.42) 0.26 (0.27) 0.17 (0.18) 0.10 (0.11)
SNP Markers          
1 DA 1 168.94 0.53 ± 0.10 T 0.53 (0.00) 0.49 (-0.04) 0.46 (-0.07) 0.43 (-0.10)
1 AI 3 304.58 0.33 ± 0.11 T 0.41 (0.08) 0.25 (-0.08) 0.16 (-0.17) 0.07 (-0.26)
1 KA 3 305.81 0.29 ± 0.11 T 0.57 (0.28) 0.48 (0.19) 0.43 (0.14) 0.33 (0.04)
27 DA 9 200.12 0.02 ± 0.13 F 0.45 (0.43) 0.32 (0.30) 0.24 (0.22) 0.16 (0.14)
67 DA 5 214.33 -0.01 ± 0.11 F 0.42 (0.43) 0.27 (0.28) 0.18 (0.19) 0.11 (0.12)
  1. *Mean ± SD over 100 replicates