Table 2 Comparison of linkage analysis results and genetic effect estimates for the naïve and three bootstrap estimates using microsatellite markers and SNPs.
From: Resampling methods to reduce the selection bias in genetic effect estimation in genome-wide scans
| Â | Â | Â | Â | Â | Â | Bootstrap estimate (bias) | |||
|---|---|---|---|---|---|---|---|---|---|
Replicate | Population | Chromosome | Highest peak (cM) | True genetic effect | T/F positive |
|
|
|
|
Microsatellite Markers | Â | Â | Â | Â | Â | Â | Â | Â | Â |
1 | DA | 1 | 169.97 | 0.49 ± 0.10 | T | 0.55 (0.06) | 0.50 (0.01) | 0.48 (-0.01) | 0.47 (-0.03) |
1 | AI | 3 | 294.68 | 0.33 ± 0.16 | T | 0.43 (0.10) | 0.31 (-0.01) | 0.25 (-0.08) | 0.19 (-0.13) |
1 | KA | 9 | 2.76 | 0.43 ± 0.11 | T | 0.49 (0.06) | 0.40 (-0.04) | 0.34 (-0.09) | 0.24 (-0.19) |
35 | DA | 6 | 192.09 | -0.01 ± 0.11 | F | 0.41 (0.42) | 0.26 (0.27) | 0.17 (0.18) | 0.10 (0.11) |
SNP Markers | Â | Â | Â | Â | Â | Â | Â | Â | Â |
1 | DA | 1 | 168.94 | 0.53 ± 0.10 | T | 0.53 (0.00) | 0.49 (-0.04) | 0.46 (-0.07) | 0.43 (-0.10) |
1 | AI | 3 | 304.58 | 0.33 ± 0.11 | T | 0.41 (0.08) | 0.25 (-0.08) | 0.16 (-0.17) | 0.07 (-0.26) |
1 | KA | 3 | 305.81 | 0.29 ± 0.11 | T | 0.57 (0.28) | 0.48 (0.19) | 0.43 (0.14) | 0.33 (0.04) |
27 | DA | 9 | 200.12 | 0.02 ± 0.13 | F | 0.45 (0.43) | 0.32 (0.30) | 0.24 (0.22) | 0.16 (0.14) |
67 | DA | 5 | 214.33 | -0.01 ± 0.11 | F | 0.42 (0.43) | 0.27 (0.28) | 0.18 (0.19) | 0.11 (0.12) |
