Investigation of altering single-nucleotide polymorphism density on the power to detect trait loci and frequency of false positive in nonparametric linkage analyses of qualitative traits

Table 6 Type I error in COGA data

Trait	SNP Set	Dz. freq.	Number of false positive below p-value criterion of^a
			0.05	0.01	0.0017	0.001	0.0001	0.000049
Dominant
Drs0041510	MS	0.14	7	2	2	2	0	0
	SNP 3 cM		10	3	1	0	0	0
	SNP 2 cM		7	1	0	0	0	0
	SNP 1 cM		15	2	1	1	0	0
	SNP 0.6 cM		12	5	1	1	0	0
	SNP 0.3 cM		14	5	2	1	0	0
	SNP 0.25		18	8	2	1	0	0
Dtsc0061481	MS	0.31	6	1	1	0	0	0
	SNP 3 cM		8	4	2	1	0	0
	SNP 2 cM		12	6	2	1	0	0
	SNP 1 cM		17	7	0	0	0	0
	SNP 0.6 cM		16	6	2	2	0	0
	SNP 0.3 cM		15	7	1	1	0	0
	SNP 0.25		24	9	3	1	0	0
Recessive
Rtsc0061581	MS	0.03	8	0	0	0	0	0
	SNP 3 cM		7	0	0	0	0	0
	SNP 2 cM		7	0	0	0	0	0
	SNP 1 cM		9	0	0	0	0	0
	SNP 0.6 cM		10	0	0	0	0	0
	SNP 0.3 cM		9	0	0	0	0	0
	SNP 0.25		13	1	0	0	0	0
Rtsc2832191	MS	0.22	6	4	2	0	0	0
	SNP 3 cM		10	3	1	0	0	0
	SNP 2 cM		12	3	2	2	0	0
	SNP 1 cM		13	4	1	1	0	0
	SNP 0.6 cM		14	6	2	1	0	0
	SNP 0.3 cM		16	6	1	1	1	0
	SNP 0.25		23	6	2	2	0	0

^aNumber of false positive regions across the 18 unlinked chromosomes with p-value below the following criteria.

ISSN: 2730-6844