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Table 3 Power in COGA data

From: Investigation of altering single-nucleotide polymorphism density on the power to detect trait loci and frequency of false positive in nonparametric linkage analyses of qualitative traits

Trait

Marker set

Dz. freq.

LOD

Minimum P-valuea

Dominant

    

   Drs0041510

MS

0.14

3.1

0.00008

 

SNP 3 cM

 

3.8

0.00001

 

SNP 2 cM

 

2.8

0.0002

 

SNP 1 cM

 

4.1

0.00001

 

SNP 0.6 cM

 

3.0

0.00008

 

SNP 0.3 cM

 

3.9

0.00001

 

SNP 0.25

 

4.1

0.00001

   Dtsc0061481

MS

0.31

1.0

0.02b

 

SNP 3 cM

 

5.7

<0.00001

 

SNP 2 cM

 

5.0

<0.00001

 

SNP 1 cM

 

5.9

<0.00001

 

SNP 0.6 cM

 

6.1

<0.00001

 

SNP 0.3 cM

 

6.3

<0.00001

 

SNP 0.25

 

6.1

<0.00001

Recessive

    

   Rtsc0061481

MS

0.03

0.81

0.03b

 

SNP 3 cM

 

1.65

0.003

 

SNP 2 cM

 

1.70

0.003

 

SNP 1 cM

 

1.68

0.002

 

SNP 0.6 cM

 

1.68

0.003

 

SNP 0.3 cM

 

1.68

0.002

 

SNP 0.25

 

1.79

0.002

   Rtsc2832191

MS

0.22

6.0

<0.00001

 

SNP 3 cM

 

4.5

<0.00001

 

SNP 2 cM

 

6.2

<0.00001

 

SNP 1 cM

 

6.7

<0.00001

 

SNP 0.6 cM

 

7.4

<0.00001

 

SNP 0.3 cM

 

7.5

<0.00001

 

SNP 0.25

 

3.6

<0.00003

  1. aMinimum p-value within 20 cM of the "true" trait locus
  2. bMarker D13S325 located about 12.3 cM from the trait loci gave a p-value of 0.0004 for trait Dtsc0061481 and a p-value of 0.004 for trait Rtsc0061481