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Table 4 Summary of linkage results for ALDX1

From: A genome-wide linkage analysis of alcoholism on microsatellite and single-nucleotide polymorphism data, using alcohol dependence phenotypes and electroencephalogram measures

  

Affymetrix SNPs

Illumina SNPs

Microsatellites

Comb3

Chr

Location (cM)

LOD (p)

IC/Chr

LOD (p)

IC/Chr

LOD (p)

IC/Chr

LOD (p)

IC/Chr

1

(138–148)

1.060 (0.014)

0.942 (0.02)

1.330 (0.007)

0.932 (0.02)

 

0.832 (0.07)

0.950 (0.020)

0.972 (0.01)

2

(10–30)

1.140 (0.011)

0.948(0.02)

1.740 (0.002)

0.934 (0.02)

1.51 (0.004)

0.845 (0.08)

1.440 (0.005)

0.975 (0.01)

 

(114–125)

1.100 (0.012)

 

0.700 (0.040)

   

1.080 (0.013)

 
 

(134–147)

1.100 (0.012)

 

1.540 (0.004)

   

1.180 (0.010)

 
 

(228–252)

1.720 (0.002)

     

1.660 (0.003)

 

6

(20–24)

0.810 (0.030)

0.947 (0.02)

0.660 (0.040)

0.935 (0.02)

 

0.803 (0.09)

0.940 (0.020)

0.974 (0.01)

 

(183–190)

  

2.150 (0.0008)

   

1.910 (0.002)

 

7

(3–19)

1.350 (0.006)

0.944 (0.03)

2.3200 (0.0005)

0.933 (0.02)

0.69 (0.04)

0.898 (0.05)

1.720 (0.002)

0.976 (0.01)

 

(29–37)

1.170 (0.010)

 

0.760 (0.030)

   

1.060 (0.014)

 
 

(54–62)

0.980 (0.020)

 

0.740 (0.030)

 

1.22 (0.009)

 

1.230 (0.009)

 
 

(83–119)

2.2500 (0.0006)

 

1.97 (0.0013)

 

1.72 (0.002)

 

2.5200 (0.0003)

 

9

(141–142)

0.660 (0.040)

0.947 (0.02)

0.690 (0.040)

0.926 (0.02)

 

0.782 (0.10)

0.770 (0.030)

0.974 (0.01)

10

(122–128)

0.750 (0.030)

0.943 (0.02)

0.650 (0.040)

0.924 (0.03)

 

0.664 (0.08)

 

0.967 (0.01)

 

(149–179)

1.9900 (0.0012)

 

1.750 (0.002)

 

0.94 (0.02)

 

1.770 (0.002)

 

11

(117–130)

1.280 (0.008)

0.946 (0.02)

1.030 (0.015)

0.924 (0.02)

1.39 (0.006)

0.709 (0.07)

1.450 (0.005)

0.968(0.01)

12

(0–5)

1.150 (0.011)

0.944 (0.02)

 

0.929 (0.03)

 

0.816 (0.08)

 

0.974 (0.01)

 

(121–125)

0.830 (0.030)

 

0.78 (0.03)

   

0.800 (0.030)

 
 

(167–172)

0.700 (0.040)

 

0.930 (0.020)

     

13

(81–102)

1.550 (0.004)

0.945 (0.02)

1.220 (0.009)

0.931 (0.02)

 

0.802 (0.10)

1.460 (0.005)

0.972 (0.01)

17

(34–36)

 

0.922 (0.05)

 

0.914 (0.03)

1.110 (0.012)

0.694 (0.08)

0.750 (0.030)

0.961 (0.02)

 

(121–123)

  

0.800 (0.030)

     

18

(93–107)

0.960 (0.020)

0.940 (0.02)

0.720 (0.030)

0.918 (0.04)

 

0.548 (0.06)

0.910 (0.020)

0.959 (0.02)

X

(30–46)

2.0500 (0.0011)

0.915 (0.03)

1.520 (0.004)

0.902 (0.08)

 

0.744 (0.17)

1.460 (0.005)

0.947 (0.03)

  1. Summary of maximum LOD scores and the corresponding p-values (<0.05) for linkage regions for alcohol dependence phenotype ALDX1. Results are shown for microsatellites, Affymetrix SNPs, Illumina SNPs and the combined data (Comb3). The mean and standard deviation of IC are given for each chromosome. Bold text indicate the most significant region on chromosome 7.
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BMC Genomic Data

ISSN: 2730-6844

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