A simple nonparametric multipoint procedure to test for linkage through mothers or fathers as well as imprinting effects in the presence of linkage

Table 3 Sets of penetrances f_ijfor the ordered genotype ij.

Genetic models for power calculations
Model	f ₁₁	f ₂₁	f ₁₂	f ₂₂
Additive	0.18	0.48 - δ	0.48 + δ	0.78
Recessive	0.18	0.18	0.18 + δ	0.78

Differences in the penetrances of heterozygous individuals are expressed through a parameter δ that ranges from 0 to 0.3 for the additive model and from 0 to 0.6 for the recessive model. For the penetrance f_ij, allele i is received from the mother.

ISSN: 2730-6844